Zeta variant, also known as lineage P.2, [a] is a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in the state of Rio de Janeiro; it harbors the E484K mutation, but not the N501Y and K417T mutations. It evolved independently in Rio de Janeiro without being directly related to the Gamma variant from Manaus. [1] [2]
Under the simplified naming scheme proposed by the World Health Organization, P.2 was labeled "Zeta variant", and was considered a variant of interest (VOI), but not a variant of concern. [3] A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database. [4] As of July 2021, Zeta is no longer considered a variant of interest by the WHO. [5]
The Zeta genome has 3 amino acid mutations: E484K, D614G, and V1176F, all of which are found in the virus's spike protein code. [6] According to the Centers for Disease Control and Prevention, F565L has been detected in some of the Zeta variant sequences, but not all. [7]
P.2… Alias of B.1.1.28.2, Brazilian lineage
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Zeta variant, also known as lineage P.2, [a] is a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in the state of Rio de Janeiro; it harbors the E484K mutation, but not the N501Y and K417T mutations. It evolved independently in Rio de Janeiro without being directly related to the Gamma variant from Manaus. [1] [2]
Under the simplified naming scheme proposed by the World Health Organization, P.2 was labeled "Zeta variant", and was considered a variant of interest (VOI), but not a variant of concern. [3] A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database. [4] As of July 2021, Zeta is no longer considered a variant of interest by the WHO. [5]
The Zeta genome has 3 amino acid mutations: E484K, D614G, and V1176F, all of which are found in the virus's spike protein code. [6] According to the Centers for Disease Control and Prevention, F565L has been detected in some of the Zeta variant sequences, but not all. [7]
P.2… Alias of B.1.1.28.2, Brazilian lineage
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This article about the COVID-19 pandemic is a stub. You can help Wikipedia by expanding it. |