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The Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19. [1] It was first detected in Peru in August 2020. [2] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant [1] and designated it as a variant of interest. [3] It has spread to at least 30 countries [4] around the world and is known to be more resistant to neutralizing antibodies compared to other strains. [5] [6] [7] There is evidence that suggests the Lambda variant is both more infectious and resistant to vaccines than the Alpha and/or Gamma variant. [8] [9]
The Lambda genome has the following amino acid mutations, all of which are in the virus's spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N. [10]
First samples of the Lambda variant were detected in Peru in August 2020 [2] and by April 2021, over eighty percent of new cases of COVID-19 in Peru were from the new variant. [1] [12] In mid-June 2021, 90.6% of new COVID-19 cases in Arequipa and 78.1% of new cases in Cusco were the Lambda variant, according to the Peruvian Ministry of Health. [13] By this time the Lambda variant had also spread throughout South America and was detected in twenty-nine countries in total, especially in Argentina, Chile and Ecuador. [12] [14] The WHO designated the Lambda variant as a "variant of interest" on 14 June 2021. [1]
On 6 July 2021, Australia reported its first case of the Lambda variant in an overseas traveler who had been in a New South Wales quarantine hotel in April. [15]
On 19 July 2021, Texas reported its first case of the Lambda variant. [16] On 22 July 2021, Florida reported 126 cumulative confirmed cases of the Lambda variant. [17] On 28 July 2021, University of Miami researchers announced random sampling showed 3 percent of COVID-19 patients in Jackson Memorial Health System and at University of Miami's UHealth Tower were infected with it. [18] On 5 August 2021, Louisiana reported its first case of the Lambda variant. [19]
On 7 August 2021, Japan confirmed its first case of the Lambda variant, with the infected person arriving in Japan from Peru on 20 July. [20]
On 15 August 2021, the Philippines confirmed its first case of the Lambda variant. [21]
Country | Confirmed cases | Collection date |
---|---|---|
Chile | 1,489 | 13 July 2021 |
Peru | 1,480 | 15 June 2021 |
United States | 848 | 5 August 2021 |
Ecuador | 194 | 20 July 2021 |
Mexico | 189 | 14 July 2021 |
Spain | 124 | 7 July 2021 |
Argentina | 111 | 24 June 2021 |
Germany | 87 | 13 July 2021 |
France | 56 | 19 July 2021 |
Colombia | 51 | 29 June 2021 |
Israel | 25 | 9 May 2021 |
Switzerland | 8 | 25 July 2021 |
Canada | 26 | 21 June 2021 |
The Netherlands | 3 | 11 July 2021 |
Saint Kitts and Nevis | 10 | 6 June 2021 |
Belgium | 2 | 23 July 2021 |
United Kingdom | 8 | 10 July 2021 |
Italy | 12 | 26 June 2021 |
Brazil | 7 | 21 June 2021 |
India | 6 | 12 April 2021 |
Denmark | 1 | 11 August 2021 |
Sweden | 1 | 15 July 2021 |
South Africa | 3 | 14 July 2021 |
Portugal | 1 | 10 June 2021 |
Qatar | 3 | 13 April 2021 |
Latvia | 2 | 30 April 2021 |
Aruba | 2 | 2 June 2021 |
Bolivia | 1 | 2 June 2021 |
Uruguay | 1 | 15 April 2021 |
Australia | 1 | 3 April 2021 |
Lithuania | 1 | 19 May 2021 |
Norway | 1 | 7 July 2021 |
Estonia | 1 | 1 April 2021 |
Russia | 1 | 21 March 2021 |
Finland | 1 | 31 May 2021 |
Turkey | 1 | 8 February 2021 |
Bangladesh | 1 | 20 March 2021 |
Japan | 1 | 7 August 2021 |
Philippines | 1 | 15 August 2021 [23] |
Venezuela | 2 | 5 May 2021 |
Mayotte | 1 | 15 July 2021 |
El Salvador | 3 | 30 April 2021 |
Guatemala | 1 | 3 July 2021 |
Costa Rica | 4 | 20 July 2021 |
World (44 countries) | Total: 4,763 | Total as of 23 August 2021 |
Lambda has been associated with substantive rates of community transmission in multiple countries, with rising prevalence over time concurrent with increased COVID-19 incidence. The earliest sequenced samples were reported from Peru in August 2020.
The Lambda variant also contained a novel deletion (Δ246-252) and multiple nonsynonymous mutations (G75V, T76I, L452Q, F490S, D614G, and T859N) in the gene that encodes the viral spike protein.
{{
cite web}}
: CS1 maint: numeric names: authors list (
link)
Part of a series on the |
COVID-19 pandemic |
---|
|
COVID-19 portal |
The Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19. [1] It was first detected in Peru in August 2020. [2] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant [1] and designated it as a variant of interest. [3] It has spread to at least 30 countries [4] around the world and is known to be more resistant to neutralizing antibodies compared to other strains. [5] [6] [7] There is evidence that suggests the Lambda variant is both more infectious and resistant to vaccines than the Alpha and/or Gamma variant. [8] [9]
The Lambda genome has the following amino acid mutations, all of which are in the virus's spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N. [10]
First samples of the Lambda variant were detected in Peru in August 2020 [2] and by April 2021, over eighty percent of new cases of COVID-19 in Peru were from the new variant. [1] [12] In mid-June 2021, 90.6% of new COVID-19 cases in Arequipa and 78.1% of new cases in Cusco were the Lambda variant, according to the Peruvian Ministry of Health. [13] By this time the Lambda variant had also spread throughout South America and was detected in twenty-nine countries in total, especially in Argentina, Chile and Ecuador. [12] [14] The WHO designated the Lambda variant as a "variant of interest" on 14 June 2021. [1]
On 6 July 2021, Australia reported its first case of the Lambda variant in an overseas traveler who had been in a New South Wales quarantine hotel in April. [15]
On 19 July 2021, Texas reported its first case of the Lambda variant. [16] On 22 July 2021, Florida reported 126 cumulative confirmed cases of the Lambda variant. [17] On 28 July 2021, University of Miami researchers announced random sampling showed 3 percent of COVID-19 patients in Jackson Memorial Health System and at University of Miami's UHealth Tower were infected with it. [18] On 5 August 2021, Louisiana reported its first case of the Lambda variant. [19]
On 7 August 2021, Japan confirmed its first case of the Lambda variant, with the infected person arriving in Japan from Peru on 20 July. [20]
On 15 August 2021, the Philippines confirmed its first case of the Lambda variant. [21]
Country | Confirmed cases | Collection date |
---|---|---|
Chile | 1,489 | 13 July 2021 |
Peru | 1,480 | 15 June 2021 |
United States | 848 | 5 August 2021 |
Ecuador | 194 | 20 July 2021 |
Mexico | 189 | 14 July 2021 |
Spain | 124 | 7 July 2021 |
Argentina | 111 | 24 June 2021 |
Germany | 87 | 13 July 2021 |
France | 56 | 19 July 2021 |
Colombia | 51 | 29 June 2021 |
Israel | 25 | 9 May 2021 |
Switzerland | 8 | 25 July 2021 |
Canada | 26 | 21 June 2021 |
The Netherlands | 3 | 11 July 2021 |
Saint Kitts and Nevis | 10 | 6 June 2021 |
Belgium | 2 | 23 July 2021 |
United Kingdom | 8 | 10 July 2021 |
Italy | 12 | 26 June 2021 |
Brazil | 7 | 21 June 2021 |
India | 6 | 12 April 2021 |
Denmark | 1 | 11 August 2021 |
Sweden | 1 | 15 July 2021 |
South Africa | 3 | 14 July 2021 |
Portugal | 1 | 10 June 2021 |
Qatar | 3 | 13 April 2021 |
Latvia | 2 | 30 April 2021 |
Aruba | 2 | 2 June 2021 |
Bolivia | 1 | 2 June 2021 |
Uruguay | 1 | 15 April 2021 |
Australia | 1 | 3 April 2021 |
Lithuania | 1 | 19 May 2021 |
Norway | 1 | 7 July 2021 |
Estonia | 1 | 1 April 2021 |
Russia | 1 | 21 March 2021 |
Finland | 1 | 31 May 2021 |
Turkey | 1 | 8 February 2021 |
Bangladesh | 1 | 20 March 2021 |
Japan | 1 | 7 August 2021 |
Philippines | 1 | 15 August 2021 [23] |
Venezuela | 2 | 5 May 2021 |
Mayotte | 1 | 15 July 2021 |
El Salvador | 3 | 30 April 2021 |
Guatemala | 1 | 3 July 2021 |
Costa Rica | 4 | 20 July 2021 |
World (44 countries) | Total: 4,763 | Total as of 23 August 2021 |
Lambda has been associated with substantive rates of community transmission in multiple countries, with rising prevalence over time concurrent with increased COVID-19 incidence. The earliest sequenced samples were reported from Peru in August 2020.
The Lambda variant also contained a novel deletion (Δ246-252) and multiple nonsynonymous mutations (G75V, T76I, L452Q, F490S, D614G, and T859N) in the gene that encodes the viral spike protein.
{{
cite web}}
: CS1 maint: numeric names: authors list (
link)