From Wikipedia, the free encyclopedia
RacCS203 is a bat-derived strain of
severe acute respiratory syndrome–related coronavirus collected in
acuminate horseshoe bats from sites in Thailand and sequenced by Lin-Fa Wang's team. It has 91.5%
sequence similarity to
SARS-CoV-2 and is most related to the
RmYN02 strain. Its
spike protein is closely related to RmYN02's spike, both highly divergent from SARS-CoV-2's spike.
[1]
[2]
A phylogenetic tree based on whole-genome sequences of SARS-CoV-2 and related coronaviruses is:
[3]
[4]
SARS‑CoV‑2 related coronavirus
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(
Bat)
Rc-o319, 81% to SARS-CoV-2,
Rhinolophus cornutus,
Iwate, Japan
[5]
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Pangolin SARSr-CoV-GX, 85.3% to SARS-CoV-2,
Manis javanica, smuggled from Southeast Asia
[7]
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Pangolin SARSr-CoV-GD, 90.1% to SARS-CoV-2, Manis javanica, smuggled from Southeast Asia
[8]
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SARS-CoV-1, 79% to SARS-CoV-2
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SARS-CoV-2 compared to other SARSr-CoV (by nucleotide %)
[13]
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Strain
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Full-length genome
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ORF1ab
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S
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RBM
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ORF3a
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E
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M
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ORF6
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ORF7a
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ORF7b
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ORF8
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N
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ORF10
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RaTG13
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96.10%
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96.50%
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92.30%
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86.30%
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96.30%
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99.60%
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95.50%
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98.40%
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95.60%
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99.20%
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97.00%
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96.90%
|
99.20%
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RmYN02
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93.60%
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97.10%
|
72.50%
|
61.90%
|
96.40%
|
98.70%
|
94.80%
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96.80%
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96.20%
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91.00%
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48.70%
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97.30%
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99.20%
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RacCS203
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91.50%
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94.30%
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71.30%
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61.60%
|
91.90%
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99.10%
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94.60%
|
96.20%
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92.40%
|
93.90%
|
91.60%
|
93.20%
|
99.20%
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GD/1/2019
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90.20%
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90.20%
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83.70%
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86.90%
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93.20%
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99.10%
|
93.30%
|
95.70%
|
93.40%
|
91.70%
|
92.10%
|
96.20%
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99.20%
|
SL-ZC45
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87.70%
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89.00%
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75.50%
|
62.50%
|
87.80%
|
98.70%
|
93.40%
|
94.60%
|
88.80%
|
94.70%
|
88.50%
|
91.10%
|
99.20%
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SL-ZXC21
|
87.50%
|
88.70%
|
74.90%
|
61.60%
|
88.90%
|
98.70%
|
93.40%
|
94.60%
|
89.10%
|
95.50%
|
88.50%
|
91.20%
|
99.20%
|
GX-P4L
|
85.40%
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84.80%
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83.60%
|
80.00%
|
86.80%
|
97.40%
|
91.30%
|
90.90%
|
86.60%
|
83.50%
|
81.30%
|
91.00%
|
88.90%
|
GX-P5L
|
85.20%
|
84.60%
|
83.30%
|
79.90%
|
87.00%
|
97.40%
|
91.30%
|
90.90%
|
86.40%
|
83.50%
|
80.70%
|
91.00%
|
94.00%
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SARS-CoV
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79.30%
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79.70%
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72.30%
|
71.90%
|
75.30%
|
93.50%
|
85.50%
|
75.50%
|
82.10%
|
83.80%
|
45.80%
|
88.20%
|
93.20%
|
Rc-o319
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79.20%
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79.80%
|
72.20%
|
70.10%
|
83.30%
|
97.40%
|
86.60%
|
86.60%
|
78.40%
|
77.30%
|
52.30%
|
88.30%
|
94.90%
|
SARS-CoV-2 compared to other SARSr-CoV (by amino acid %)
[13]
|
|
Strain
|
Full-length genome
|
ORF1ab
|
S
|
RBM
|
ORF3a
|
E
|
M
|
ORF6
|
ORF7a
|
ORF7b
|
ORF8
|
N
|
ORF10
|
RaTG13
|
|
98.50%
|
97.30%
|
90.10%
|
97.80%
|
100.00%
|
99.60%
|
100.00%
|
97.50%
|
97.70%
|
95.00%
|
99.10%
|
97.40%
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RmYN02
|
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98.80%
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72.40%
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63.20%
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96.70%
|
100.00%
|
98.70%
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96.70%
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95.90%
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83.70%
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28.20%
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98.60%
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97.40%
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RacCS203
|
|
97.30%
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72.30%
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63.70%
|
97.50%
|
100.00%
|
99.10%
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98.40%
|
95.90%
|
93.00%
|
94.20%
|
95.70%
|
-
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GD/1/2019
|
|
96.70%
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90.00%
|
96.90%
|
97.10%
|
100.00%
|
98.70%
|
96.70%
|
97.50%
|
95.40%
|
95.00%
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97.90%
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97.40%
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SL-ZC45
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95.60%
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80.20%
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65.90%
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90.90%
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100.00%
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98.70%
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93.40%
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87.60%
|
93.00%
|
94.20%
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94.30%
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97.40%
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SL-ZXC21
|
|
95.20%
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79.70%
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65.90%
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92.00%
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100.00%
|
98.70%
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93.40%
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88.40%
|
93.00%
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94.20%
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94.30%
|
-
|
GX-P4L
|
|
92.50%
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92.30%
|
86.60%
|
89.50%
|
100.00%
|
98.20%
|
95.10%
|
88.40%
|
-
|
87.60%
|
93.60%
|
73.70%
|
GX-P5L
|
|
92.50%
|
92.40%
|
86.60%
|
89.80%
|
100.00%
|
98.20%
|
95.10%
|
88.40%
|
72.10%
|
87.60%
|
93.80%
|
84.20%
|
SARS-CoV
|
|
86.10%
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75.80%
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73.10%
|
72.40%
|
94.70%
|
90.50%
|
67.20%
|
85.30%
|
81.40%
|
-
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90.50%
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81.60%
|
Rc-o319
|
|
87.60%
|
76.20%
|
73.50%
|
87.00%
|
98.70%
|
91.00%
|
83.60%
|
73.80%
|
69.80%
|
26.80%
|
89.50%
|
86.80%
|
-
RaTG13, 96.2% similarity to SARS-COV-2
-
RmYN02, 93.3% similarity to SARS-COV-2
-
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doi:
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PMC
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^
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a
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PMC
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PMID
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