40S ribosomal protein S14 is a
protein that in humans is encoded by the RPS14gene.[5][6][7]
Ribosomes, the
organelles that
catalyzeprotein synthesis, consist of a
small 40S subunit and a
large 60S subunit. Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the
cytoplasm.
Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome. In
Chinese hamster ovary cells, mutations in this gene can lead to resistance to
emetine, a protein synthesis inhibitor.[7]
Matoba R, Okubo K, Hori N, et al. (1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207.
doi:
10.1016/0378-1119(94)90293-3.
PMID8076819.
40S ribosomal protein S14 is a
protein that in humans is encoded by the RPS14gene.[5][6][7]
Ribosomes, the
organelles that
catalyzeprotein synthesis, consist of a
small 40S subunit and a
large 60S subunit. Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the
cytoplasm.
Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed
pseudogenes of this gene dispersed through the genome. In
Chinese hamster ovary cells, mutations in this gene can lead to resistance to
emetine, a protein synthesis inhibitor.[7]
Matoba R, Okubo K, Hori N, et al. (1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207.
doi:
10.1016/0378-1119(94)90293-3.
PMID8076819.