60S ribosomal protein L27a is a
protein that in humans is encoded by the RPL27Agene.[5][6][7]
Ribosomes, the
organelles that catalyze
protein synthesis, consist of a small
40S subunit and a large
60S subunit. Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the
cytoplasm. Variable expression of this gene in
colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed
pseudogenes derived from this gene are dispersed through the genome.[7]
Kusuda J, Hirai M, Tanuma R, et al. (1999). "Genomic structure and chromosome location of RPL27A/Rpl27a, the genes encoding human and mouse ribosomal protein L27A". Cytogenet. Cell Genet. 85 (3–4): 248–251.
doi:
10.1159/000015303.
PMID10449908.
S2CID7314458.
60S ribosomal protein L27a is a
protein that in humans is encoded by the RPL27Agene.[5][6][7]
Ribosomes, the
organelles that catalyze
protein synthesis, consist of a small
40S subunit and a large
60S subunit. Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the
cytoplasm. Variable expression of this gene in
colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed
pseudogenes derived from this gene are dispersed through the genome.[7]
Kusuda J, Hirai M, Tanuma R, et al. (1999). "Genomic structure and chromosome location of RPL27A/Rpl27a, the genes encoding human and mouse ribosomal protein L27A". Cytogenet. Cell Genet. 85 (3–4): 248–251.
doi:
10.1159/000015303.
PMID10449908.
S2CID7314458.