Large ribosomal subunit protein uL22 is a
protein that in humans is encoded by the RPL17gene.[5][6][7]
Ribosomes, the
organelles that catalyze
protein synthesis, consist of a small
40S subunit and a large
60S subunit. Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the
cytoplasm. This gene has been referred to as RPL23 because the encoded protein shares
amino acid identity with ribosomal protein L23 from Haloarcula marismortui; however, its official symbol is RPL17. Two alternative
splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome.[7]
Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18.
doi:
10.1038/sj.onc.1206406.
PMID12761501.
S2CID38880905.
Odintsova TI, Müller EC, Ivanov AV, et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58.
doi:
10.1023/A:1025068419698.
PMID12962325.
S2CID10710245.
Large ribosomal subunit protein uL22 is a
protein that in humans is encoded by the RPL17gene.[5][6][7]
Ribosomes, the
organelles that catalyze
protein synthesis, consist of a small
40S subunit and a large
60S subunit. Together these subunits are composed of 4
RNA species and approximately 80 structurally distinct proteins. This gene encodes a
ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the
cytoplasm. This gene has been referred to as RPL23 because the encoded protein shares
amino acid identity with ribosomal protein L23 from Haloarcula marismortui; however, its official symbol is RPL17. Two alternative
splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple
processed pseudogenes of this gene dispersed through the genome.[7]
Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18.
doi:
10.1038/sj.onc.1206406.
PMID12761501.
S2CID38880905.
Odintsova TI, Müller EC, Ivanov AV, et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58.
doi:
10.1023/A:1025068419698.
PMID12962325.
S2CID10710245.