An oxytocin receptor agonist is a compound that acts as an agonist of the oxytocin receptor. [1] [2] Examples include peptide oxytocin receptor agonists like oxytocin (Pitocin, Syntocinon), carbetocin (Duratocin, Pabal), and demoxytocin (Sandopart) and small-molecule oxytocin receptor agonists like TC OT 39, WAY-267464, and LIT-001. [1] [2] Oxytocin receptor agonists are used medically to induce labor, promote lactation, and for other uses. [3] In addition, oxytocin receptor agonists are of theoretical interest for the potential treatment of social disorders, such as autism and social anxiety. [1] [2] Small-molecule oxytocin receptor agonists are considered to be more promising for such uses due to better pharmacokinetic profiles, such as blood–brain barrier permeability, elimination half-lives, and potential for oral bioavailability. [1] [2]
An oxytocin receptor agonist is a compound that acts as an agonist of the oxytocin receptor. [1] [2] Examples include peptide oxytocin receptor agonists like oxytocin (Pitocin, Syntocinon), carbetocin (Duratocin, Pabal), and demoxytocin (Sandopart) and small-molecule oxytocin receptor agonists like TC OT 39, WAY-267464, and LIT-001. [1] [2] Oxytocin receptor agonists are used medically to induce labor, promote lactation, and for other uses. [3] In addition, oxytocin receptor agonists are of theoretical interest for the potential treatment of social disorders, such as autism and social anxiety. [1] [2] Small-molecule oxytocin receptor agonists are considered to be more promising for such uses due to better pharmacokinetic profiles, such as blood–brain barrier permeability, elimination half-lives, and potential for oral bioavailability. [1] [2]