From Wikipedia, the free encyclopedia
Nucleus ambiguus
Transverse section of medulla oblongata below the middle of the olive. ("Nucleus ambiguus" labeled at center right.)
Details
Identifiers
Latinnucleus ambiguus
NeuroNames 765
NeuroLex ID birnlex_2650
TA98 A14.1.04.253
TA2 6011
FMA 54588
Anatomical terms of neuroanatomy

The nucleus ambiguus is a group of large motor neurons situated in the reticular formation of the medulla oblongata of the brainstem. [1] It represents a shared cranial nerve nucleus of the glossopharyngeal nerve (CN IX), and vagus nerve (CN X); [2]: 103  the cranial root of accessory nerve (CN XI) is now also considered as (displaced) fibers of CN X arising from the caudal nucleus ambiguus to travel some distance with those of the (spinal root of) CN XI before joining the main CN X. [2]: 345 

Lower motor neurons of the nucleus ambiguus ipsilaterally innervate muscles of the soft palate, pharynx, larynx, and upper esophagus; they are thus involved in speech and swallowing.[ citation needed]

Anatomy

The nucleus is situated dorsal/posterior to the inferior olivary nucleus, and lateral to the medial lemniscus. [2]: 103  It is situated near the facial motor nucleus. [1]

Efferent fibers from the nucleus ambiguus pass dorsomedially before curving laterally. The rostral portion of nucleus ambiguus contributes fibers to CN IX, and the caudal portion to CN X. [1]

Connections

The nucleus receives bilateral (but mostly contralateral) upper motor neuron afferents via corticonuclear fibers. [1] The fibers destined for the nucleus ambiguus mostly diverge from the corticonuclaer tract at the level of the caudal pons and rostral medulla oblongata, however, some descend alongside the corticospinal tract to reach and decussate at the pyramidal decussation before reascending to reach the nucleus ambiguus. [2]: 240 

The nucleus also forms reciprocal connections with other nuclei of the brainstem. [1]

Innervation

This nucleus gives rise to the branchial efferent motor fibers of the CN X innervating laryngeal and pharyngeal muscles, and musculus uvulae; [3] axons from the nucleus ambiguus passing in the CN IX innervate the stylopharyngeus muscle.[ citation needed]

Clinical significance

Lesions of nucleus ambiguus result in dysphagia, dysphonia, [2]: 115  and contralateral deviation of the uvula. [2]: 118 

Additional images

See also

References

  1. ^ a b c d e Standring, Susan (2020). Gray's Anatomy: The Anatomical Basis of Clinical Practice (42th ed.). New York: Elsevier. p. 449. ISBN  978-0-7020-7707-4. OCLC  1201341621.
  2. ^ a b c d e f Patestas, Maria A.; Gartner, Leslie P. (2016). A Textbook of Neuroanatomy (2nd ed.). Hoboken, New Jersey: Wiley-Blackwell. ISBN  978-1-118-67746-9.
  3. ^ Petko, Bogdana; Tadi, Prasanna (2024), "Neuroanatomy, Nucleus Ambiguus", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID  31613524, retrieved 2024-05-03
From Wikipedia, the free encyclopedia
Nucleus ambiguus
Transverse section of medulla oblongata below the middle of the olive. ("Nucleus ambiguus" labeled at center right.)
Details
Identifiers
Latinnucleus ambiguus
NeuroNames 765
NeuroLex ID birnlex_2650
TA98 A14.1.04.253
TA2 6011
FMA 54588
Anatomical terms of neuroanatomy

The nucleus ambiguus is a group of large motor neurons situated in the reticular formation of the medulla oblongata of the brainstem. [1] It represents a shared cranial nerve nucleus of the glossopharyngeal nerve (CN IX), and vagus nerve (CN X); [2]: 103  the cranial root of accessory nerve (CN XI) is now also considered as (displaced) fibers of CN X arising from the caudal nucleus ambiguus to travel some distance with those of the (spinal root of) CN XI before joining the main CN X. [2]: 345 

Lower motor neurons of the nucleus ambiguus ipsilaterally innervate muscles of the soft palate, pharynx, larynx, and upper esophagus; they are thus involved in speech and swallowing.[ citation needed]

Anatomy

The nucleus is situated dorsal/posterior to the inferior olivary nucleus, and lateral to the medial lemniscus. [2]: 103  It is situated near the facial motor nucleus. [1]

Efferent fibers from the nucleus ambiguus pass dorsomedially before curving laterally. The rostral portion of nucleus ambiguus contributes fibers to CN IX, and the caudal portion to CN X. [1]

Connections

The nucleus receives bilateral (but mostly contralateral) upper motor neuron afferents via corticonuclear fibers. [1] The fibers destined for the nucleus ambiguus mostly diverge from the corticonuclaer tract at the level of the caudal pons and rostral medulla oblongata, however, some descend alongside the corticospinal tract to reach and decussate at the pyramidal decussation before reascending to reach the nucleus ambiguus. [2]: 240 

The nucleus also forms reciprocal connections with other nuclei of the brainstem. [1]

Innervation

This nucleus gives rise to the branchial efferent motor fibers of the CN X innervating laryngeal and pharyngeal muscles, and musculus uvulae; [3] axons from the nucleus ambiguus passing in the CN IX innervate the stylopharyngeus muscle.[ citation needed]

Clinical significance

Lesions of nucleus ambiguus result in dysphagia, dysphonia, [2]: 115  and contralateral deviation of the uvula. [2]: 118 

Additional images

See also

References

  1. ^ a b c d e Standring, Susan (2020). Gray's Anatomy: The Anatomical Basis of Clinical Practice (42th ed.). New York: Elsevier. p. 449. ISBN  978-0-7020-7707-4. OCLC  1201341621.
  2. ^ a b c d e f Patestas, Maria A.; Gartner, Leslie P. (2016). A Textbook of Neuroanatomy (2nd ed.). Hoboken, New Jersey: Wiley-Blackwell. ISBN  978-1-118-67746-9.
  3. ^ Petko, Bogdana; Tadi, Prasanna (2024), "Neuroanatomy, Nucleus Ambiguus", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID  31613524, retrieved 2024-05-03

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