Microvenular hemangioma | |
---|---|
Other names | Microcapillary hemangioma [1] |
Specialty |
Oncology
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Microvenular hemangioma is an acquired benign vascular tumor that presents as an asymptomatic, slowly growing, 0.5- to 2.0 cm reddish lesion on the forearms or other sites of young to middle-aged adults. [2] The cause of microvenular hemangioma is unknown, however it has been associated with immunosuppression.
Microvenular hemangioma appears as slow-growing, frequently numerous lesions, erythematous, violaceous, or moderately pruriginous macules, papules, or nodules without any symptoms. [3] They usually appear on the forearm. There have also been reports of lesions on the soles of the feet, forehead, legs, and chest. [4]
Although the exact cause of microvenular hemangioma is uncertain, it has been found in certain instances during pregnancy or after changes in hormonal contraception. [5] In certain circumstances, imbalanced sex hormones could potentially be the cause. [6] Microvenular hemangioma has also been associated with immunosuppression. [7]
Multiple distinct red globules are seen under a microscope, and a finely pigmented network is seen around the periphery. [8] Histologically, microvenular hemangioma is made up of venules with thin walls that branch erratically and have barely noticeable vascular lumina. The dermis's collagen bundles are thickened. [6] Pericytes envelop the endothelial cells, [9] which can exhibit a combination of plump and flat cells without pleomorphism or mitotic patterns. [10]
Immunohistochemically, an microvenular hemangioma's endothelial cells show positive staining for CD31, CD34, and factor VIII, while its pericytes show positive staining for SMA. [8] [11] However, neither cell shows positive staining for podoplanin. [12]
The differential diagnosis for microvenular hemangioma includes acquired ( tufted) angioma, Kaposi sarcoma, Kaposiform hemangioendothelioma, and sclerosing hemangioma. [13]
The treatment for microvenular hemangioma is surgical excision. [13]
Microvenular hemangioma | |
---|---|
Other names | Microcapillary hemangioma [1] |
Specialty |
Oncology
![]() |
Microvenular hemangioma is an acquired benign vascular tumor that presents as an asymptomatic, slowly growing, 0.5- to 2.0 cm reddish lesion on the forearms or other sites of young to middle-aged adults. [2] The cause of microvenular hemangioma is unknown, however it has been associated with immunosuppression.
Microvenular hemangioma appears as slow-growing, frequently numerous lesions, erythematous, violaceous, or moderately pruriginous macules, papules, or nodules without any symptoms. [3] They usually appear on the forearm. There have also been reports of lesions on the soles of the feet, forehead, legs, and chest. [4]
Although the exact cause of microvenular hemangioma is uncertain, it has been found in certain instances during pregnancy or after changes in hormonal contraception. [5] In certain circumstances, imbalanced sex hormones could potentially be the cause. [6] Microvenular hemangioma has also been associated with immunosuppression. [7]
Multiple distinct red globules are seen under a microscope, and a finely pigmented network is seen around the periphery. [8] Histologically, microvenular hemangioma is made up of venules with thin walls that branch erratically and have barely noticeable vascular lumina. The dermis's collagen bundles are thickened. [6] Pericytes envelop the endothelial cells, [9] which can exhibit a combination of plump and flat cells without pleomorphism or mitotic patterns. [10]
Immunohistochemically, an microvenular hemangioma's endothelial cells show positive staining for CD31, CD34, and factor VIII, while its pericytes show positive staining for SMA. [8] [11] However, neither cell shows positive staining for podoplanin. [12]
The differential diagnosis for microvenular hemangioma includes acquired ( tufted) angioma, Kaposi sarcoma, Kaposiform hemangioendothelioma, and sclerosing hemangioma. [13]
The treatment for microvenular hemangioma is surgical excision. [13]