Glomeruloid hemangioma | |
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Specialty | Dermatology |
Glomeruloid hemangioma is a distinctive vascular tumor first described in 1990 when found to be associated with POEMS syndrome and Castleman disease. [1] [2] Glomeruloid hemangiomas can manifest as wine-red sessile or pedunculated papules, papulonodules, subcutaneous bluish compressible tumors, or small, firm, reddish-violaceous, dome-shaped papules.
Glomeruloid hemangiomas can manifest as wine-red sessile or pedunculated papules, papulonodules, subcutaneous bluish compressible tumors, or small, firm, reddish-violaceous, dome-shaped papules. [3] They mostly reside on the trunk and proximal limbs and range in size from a few millimeters to a few centimeters in diameter. [4] [5] There have also been rare reports of glomeruloid hemangioma impacting the face. [6] [7] There have also been reports of eruptive angiomatous lesions, which resemble eruptive histiocytomas. [8]
Glomeruloid hemangiomas are most commonly associated with POEMS syndrome, occurring in up to 45% of individuals with POEMS syndrome. [9] Glomeruloid hemangiomas have also been associated with TAFRO syndrome. [10] Rarely glomeruloid hemangiomas can occur in individuals with no systematic conditions. [11]
The histopathologic examination displays well-defined, dispersed dermal structures in different sizes that have resemblance to renal glomeruli. The central vessel is bigger and has a sinusoidal appearance, and it is surrounded by a network of small capillary vessels on the periphery. [12]
Glomeruloid hemangioma | |
---|---|
Specialty | Dermatology |
Glomeruloid hemangioma is a distinctive vascular tumor first described in 1990 when found to be associated with POEMS syndrome and Castleman disease. [1] [2] Glomeruloid hemangiomas can manifest as wine-red sessile or pedunculated papules, papulonodules, subcutaneous bluish compressible tumors, or small, firm, reddish-violaceous, dome-shaped papules.
Glomeruloid hemangiomas can manifest as wine-red sessile or pedunculated papules, papulonodules, subcutaneous bluish compressible tumors, or small, firm, reddish-violaceous, dome-shaped papules. [3] They mostly reside on the trunk and proximal limbs and range in size from a few millimeters to a few centimeters in diameter. [4] [5] There have also been rare reports of glomeruloid hemangioma impacting the face. [6] [7] There have also been reports of eruptive angiomatous lesions, which resemble eruptive histiocytomas. [8]
Glomeruloid hemangiomas are most commonly associated with POEMS syndrome, occurring in up to 45% of individuals with POEMS syndrome. [9] Glomeruloid hemangiomas have also been associated with TAFRO syndrome. [10] Rarely glomeruloid hemangiomas can occur in individuals with no systematic conditions. [11]
The histopathologic examination displays well-defined, dispersed dermal structures in different sizes that have resemblance to renal glomeruli. The central vessel is bigger and has a sinusoidal appearance, and it is surrounded by a network of small capillary vessels on the periphery. [12]