From Wikipedia, the free encyclopedia
malate dehydrogenase (quinone)
Identifiers
EC no. 1.1.5.4
CAS no. 71822-24-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a malate dehydrogenase (quinone) ( EC 1.1.5.4), formerly malate dehydrogenase (acceptor) (EC 1.1.99.16), is an enzyme that catalyzes the chemical reaction

(S)-malate + a quinone oxaloacetate + reduced quinone

Thus, the two substrates of this enzyme are (S)-malate and a quinone, whereas its two products are oxaloacetate and reduced quinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a quinone as acceptor. The systematic name of this enzyme class is (S)-malate:quinone oxidoreductase. Other names in common use include FAD-dependent malate-vitamin K reductase, malate-vitamin K reductase, and (S)-malate:(quinone) oxidoreductase. This enzyme participates in pyruvate metabolism. It employs one cofactor, FAD.

References

  • Imai D; Brodie AF (1973). "A phospholipid-requiring enzyme, malate-vitamin K reductase". J. Biol. Chem. 248 (21): 7487–7494. doi: 10.1016/S0021-9258(19)43316-4.
  • Imai T (1978). "FAD-dependent malate dehydrogenase, a phospholipid-requiring enzyme from Mycobacterium sp. strain Takeo. Purification and some properties". Biochim. Biophys. Acta. 523 (1): 37–46. doi: 10.1016/0005-2744(78)90006-2. PMID  629992.
  • Prasada Reddy TL, Suryanarayana Murthy P, Venkitasubramanian TA (1975). "Variations in the pathways of malate oxidation and phosphorylation in different species of Mycobacteria". Biochim. Biophys. Acta. 376 (2): 210–8. doi: 10.1016/0005-2728(75)90012-2. PMID  234747.


From Wikipedia, the free encyclopedia
malate dehydrogenase (quinone)
Identifiers
EC no. 1.1.5.4
CAS no. 71822-24-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a malate dehydrogenase (quinone) ( EC 1.1.5.4), formerly malate dehydrogenase (acceptor) (EC 1.1.99.16), is an enzyme that catalyzes the chemical reaction

(S)-malate + a quinone oxaloacetate + reduced quinone

Thus, the two substrates of this enzyme are (S)-malate and a quinone, whereas its two products are oxaloacetate and reduced quinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a quinone as acceptor. The systematic name of this enzyme class is (S)-malate:quinone oxidoreductase. Other names in common use include FAD-dependent malate-vitamin K reductase, malate-vitamin K reductase, and (S)-malate:(quinone) oxidoreductase. This enzyme participates in pyruvate metabolism. It employs one cofactor, FAD.

References

  • Imai D; Brodie AF (1973). "A phospholipid-requiring enzyme, malate-vitamin K reductase". J. Biol. Chem. 248 (21): 7487–7494. doi: 10.1016/S0021-9258(19)43316-4.
  • Imai T (1978). "FAD-dependent malate dehydrogenase, a phospholipid-requiring enzyme from Mycobacterium sp. strain Takeo. Purification and some properties". Biochim. Biophys. Acta. 523 (1): 37–46. doi: 10.1016/0005-2744(78)90006-2. PMID  629992.
  • Prasada Reddy TL, Suryanarayana Murthy P, Venkitasubramanian TA (1975). "Variations in the pathways of malate oxidation and phosphorylation in different species of Mycobacteria". Biochim. Biophys. Acta. 376 (2): 210–8. doi: 10.1016/0005-2728(75)90012-2. PMID  234747.



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