Identifiers | |
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CAS Number | |
ChemSpider | |
ChEMBL | |
Chemical and physical data | |
Formula | C15H9FN2 |
Molar mass | 236.244 |
3D model ( JSmol) | |
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MFZ 10-7 (3-fluoro-5-((6-methylpyridin-2-yl)ethynyl)benzonitrile) is a drug with potential applications in the treatment of addiction, which acts as a negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5). Others of the kind, namely MPEP & MTEP, are not considered to have translational potential for human use due to off-target effects and short half-lives. Drugs of this kind have been used to offset craving for drugs of abuse such as cocaine in in vivo animal administration models. [1]
Identifiers | |
---|---|
| |
CAS Number | |
ChemSpider | |
ChEMBL | |
Chemical and physical data | |
Formula | C15H9FN2 |
Molar mass | 236.244 |
3D model ( JSmol) | |
| |
|
MFZ 10-7 (3-fluoro-5-((6-methylpyridin-2-yl)ethynyl)benzonitrile) is a drug with potential applications in the treatment of addiction, which acts as a negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGluR5). Others of the kind, namely MPEP & MTEP, are not considered to have translational potential for human use due to off-target effects and short half-lives. Drugs of this kind have been used to offset craving for drugs of abuse such as cocaine in in vivo animal administration models. [1]