From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Lysine-specific demethylase 4B is an
enzyme that in humans is encoded by the KDM4B
gene .
[5]
[6]
[7] KDM4B belongs to the
alpha-ketoglutarate-dependent hydroxylase superfamily.
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000127663 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000024201 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999).
"Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (6): 355–64.
doi :
10.1093/dnares/5.6.355 .
PMID
10048485 .
^ Katoh M, Katoh M (May 2004). "Identification and characterization of JMJD2 family genes in silico". Int J Oncol . 24 (6): 1623–8.
doi :
10.3892/ijo.25.3.759 .
PMID
15138608 .
^
"Entrez Gene: JMJD2B jumonji domain containing 2B" .
Further reading
Nakajima D, Okazaki N, Yamakawa H, et al. (2003).
"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones" . DNA Res . 9 (3): 99–106.
doi :
10.1093/dnares/9.3.99 .
PMID
12168954 .
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem . 236 (1): 107–13.
doi :
10.1006/abio.1996.0138 .
PMID
8619474 .
Yu W, Andersson B, Worley KC, et al. (1997).
"Large-scale concatenation cDNA sequencing" . Genome Res . 7 (4): 353–8.
doi :
10.1101/gr.7.4.353 .
PMC
139146 .
PMID
9110174 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Grimwood J, Gordon LA, Olsen A, et al. (2004).
"The DNA sequence and biology of human chromosome 19" . Nature . 428 (6982): 529–35.
Bibcode :
2004Natur.428..529G .
doi :
10.1038/nature02399 .
PMID
15057824 .
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
"Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5.
Bibcode :
2004PNAS..10112130B .
doi :
10.1073/pnas.0404720101 .
PMC
514446 .
PMID
15302935 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Gray SG, Iglesias AH, Lizcano F, et al. (2005).
"Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein" . J. Biol. Chem . 280 (31): 28507–18.
doi :
10.1074/jbc.M413687200 .
PMID
15927959 .
Whetstine JR, Nottke A, Lan F, et al. (2006).
"Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases" . Cell . 125 (3): 467–81.
doi :
10.1016/j.cell.2006.03.028 .
PMID
16603238 .
S2CID
14461740 .
Katoh Y, Katoh M (2007).
"Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells" . Int. J. Mol. Med . 20 (2): 269–73.
doi :
10.3892/ijmm.20.2.269 .
PMID
17611647 .
Deng P, Yuan Q, Cheng Y, et al. (2021).
"Loss of KDM4B exacerbates bone-fat imbalance and mesenchymal stromal cell exhaustion in skeletal aging" . Cell Stem Cell . 28 (6): 1057–1073.e7.
doi :
10.1016/j.stem.2021.01.010 .
PMC
8178178 .
PMID
33571444 .
Activity Regulation Classification Kinetics Types