Jonathan Hodgkin | |
|---|---|
| Born | Jonathan Alan Hodgkin 1949 (age 74–75) [3] |
| Alma mater |
University of Oxford (
BA) University of Cambridge ( PhD) |
| Awards | Edward Novitski Prize (2017) [1] |
| Scientific career | |
| Institutions | Laboratory of Molecular Biology [2] |
| Thesis | Genetic and Anatomical Aspects of the Caenorhabditis elegans Male (1974) |
| Notable students | Magdalena Skipper [2] |
| Website |
www |
Jonathan Alan Hodgkin (born 1949) [3] FRS is a British biochemist, Professor of Genetics at the University of Oxford [4] and an emeritus fellow of Keble College, Oxford. [5]
Education
Hodgkin was educated at the University of Oxford where he graduated in 1971.[ citation needed] He was awarded a PhD from the University of Cambridge in 1974 for research on the genetics of the worm Caenorhabditis elegans. [6]
Career and research
Hodgkin was a scientist at the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge. [7] [3] Hodgkin was one of the earliest researchers to explore the genetics of development in the nematode worm Caenorhabditis elegans. [8] He first unraveled the genetic and maturational events in worm sex determination before extending his interest to other developmental pathways, behaviour and immunity. [8]
Most Caenorhabditis elegans worms are self-fertilizing hermaphrodites, with two X chromosomes, but X0 males can also arise spontaneously, permitting genetic crosses. [8] Hodgkin used genetic mutations in this tiny, fast-breeding species to define the regulatory cascade of genes that controls the development of male or hermaphrodite characteristics providing a model for approaching development in other species. [8]
Since 2000, Hodgkin has focused on the nematode's response to attack by bacteria, exploring highly conserved pathways of innate immunity that are also relevant to development. [8] Through microarray analysis, he has identified antibacterial factors produced by the worm that could be candidates for new antibiotics. [8] He has also discovered novel pathogenic bacteria that attack nematodes, which may have potential as biological pest control agents against parasitic nematodes. [8]
Awards and honours
Hodgkin was elected a Fellow of the Royal Society (FRS) in 1990. [8] In 2011, he received The Genetics Society Medal. [8] Hodgkin was a member of the Faculty of 1000. [9] He was awarded the Edward Novitski Prize by the Genetics Society of America in 2017. [1] [10]
Personal life
Hodgkin is the son of Nobel laureate Alan Lloyd Hodgkin and the editor Marni Hodgkin. [3]
References
- ^
a
b Hodgkin, J (2017), "Frontiers of Knowledge: An Interview with 2017 Edward Novitski Prize Recipient Jonathan Hodgkin", Genetics, 207 (4): 1219–1220,
doi:
10.1534/genetics.117.300400 (inactive 31 January 2024),
ISSN
0016-6731,
PMC
5714439,
PMID
29203697
{{ citation}}: CS1 maint: DOI inactive as of January 2024 ( link) - ^
a
b Skipper, M.; Milne, C. A.; Hodgkin, J. (1999).
"Genetic and molecular analysis of fox-1, a numerator element involved in Caenorhabditis elegans primary sex determination". Genetics. 151 (2): 617–631.
doi:
10.1093/genetics/151.2.617.
PMC
1460491.
PMID
9927456.
- ^ a b c d Anon (2017). "Hodgkin, Prof. Jonathan Alan". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi: 10.1093/ww/9780199540884.013.U20378. (Subscription or UK public library membership required.)
- ^ Jonathan Hodgkin publications indexed by the Scopus bibliographic database. (subscription required)
- ^ "Professor Jonathan Hodgkin". keble.ox.ac.uk. Keble College, Oxford. Retrieved February 14, 2012.
- ^ Hodgkin, Jonathan Alan (1974). Genetic and Anatomical Aspects of the Caenorhabditis elegans Male. jisc.ac.uk (PhD thesis). University of Cambridge. OCLC 500473570. EThOS uk.bl.ethos.459309.
- ^ Hodgkin, Jonathan (2004). "Jonathan Hodgkin". Current Biology. 14 (7): R259–60. doi: 10.1016/j.cub.2004.03.015. PMID 15062112. S2CID 8464632.
- ^
a
b
c
d
e
f
g
h
i Anon (1990).
"Professor Jonathan Hodgkin FRS". royalsociety.org. London:
Royal Society. Archived from
the original on 2015-11-17. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” -- Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
- ^ "Jonathan Hodgkin: Former Member in Developmental Molecular Mechanisms". f1000.com. F1000. Retrieved 2012-02-14.
- ^ "Jonathan Hodgkin awarded the 2017 Novitski Prize". genestogenomes.org. 21 March 2017. Retrieved 16 April 2019.
This article incorporates
text available under the
CC BY 4.0 license.
| International | |
|---|---|
| National | |
| Academics | |
Jonathan Hodgkin | |
|---|---|
| Born | Jonathan Alan Hodgkin 1949 (age 74–75) [3] |
| Alma mater |
University of Oxford (
BA) University of Cambridge ( PhD) |
| Awards | Edward Novitski Prize (2017) [1] |
| Scientific career | |
| Institutions | Laboratory of Molecular Biology [2] |
| Thesis | Genetic and Anatomical Aspects of the Caenorhabditis elegans Male (1974) |
| Notable students | Magdalena Skipper [2] |
| Website |
www |
Jonathan Alan Hodgkin (born 1949) [3] FRS is a British biochemist, Professor of Genetics at the University of Oxford [4] and an emeritus fellow of Keble College, Oxford. [5]
Education
Hodgkin was educated at the University of Oxford where he graduated in 1971.[ citation needed] He was awarded a PhD from the University of Cambridge in 1974 for research on the genetics of the worm Caenorhabditis elegans. [6]
Career and research
Hodgkin was a scientist at the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge. [7] [3] Hodgkin was one of the earliest researchers to explore the genetics of development in the nematode worm Caenorhabditis elegans. [8] He first unraveled the genetic and maturational events in worm sex determination before extending his interest to other developmental pathways, behaviour and immunity. [8]
Most Caenorhabditis elegans worms are self-fertilizing hermaphrodites, with two X chromosomes, but X0 males can also arise spontaneously, permitting genetic crosses. [8] Hodgkin used genetic mutations in this tiny, fast-breeding species to define the regulatory cascade of genes that controls the development of male or hermaphrodite characteristics providing a model for approaching development in other species. [8]
Since 2000, Hodgkin has focused on the nematode's response to attack by bacteria, exploring highly conserved pathways of innate immunity that are also relevant to development. [8] Through microarray analysis, he has identified antibacterial factors produced by the worm that could be candidates for new antibiotics. [8] He has also discovered novel pathogenic bacteria that attack nematodes, which may have potential as biological pest control agents against parasitic nematodes. [8]
Awards and honours
Hodgkin was elected a Fellow of the Royal Society (FRS) in 1990. [8] In 2011, he received The Genetics Society Medal. [8] Hodgkin was a member of the Faculty of 1000. [9] He was awarded the Edward Novitski Prize by the Genetics Society of America in 2017. [1] [10]
Personal life
Hodgkin is the son of Nobel laureate Alan Lloyd Hodgkin and the editor Marni Hodgkin. [3]
References
- ^
a
b Hodgkin, J (2017), "Frontiers of Knowledge: An Interview with 2017 Edward Novitski Prize Recipient Jonathan Hodgkin", Genetics, 207 (4): 1219–1220,
doi:
10.1534/genetics.117.300400 (inactive 31 January 2024),
ISSN
0016-6731,
PMC
5714439,
PMID
29203697
{{ citation}}: CS1 maint: DOI inactive as of January 2024 ( link) - ^
a
b Skipper, M.; Milne, C. A.; Hodgkin, J. (1999).
"Genetic and molecular analysis of fox-1, a numerator element involved in Caenorhabditis elegans primary sex determination". Genetics. 151 (2): 617–631.
doi:
10.1093/genetics/151.2.617.
PMC
1460491.
PMID
9927456.
- ^ a b c d Anon (2017). "Hodgkin, Prof. Jonathan Alan". Who's Who (online Oxford University Press ed.). Oxford: A & C Black. doi: 10.1093/ww/9780199540884.013.U20378. (Subscription or UK public library membership required.)
- ^ Jonathan Hodgkin publications indexed by the Scopus bibliographic database. (subscription required)
- ^ "Professor Jonathan Hodgkin". keble.ox.ac.uk. Keble College, Oxford. Retrieved February 14, 2012.
- ^ Hodgkin, Jonathan Alan (1974). Genetic and Anatomical Aspects of the Caenorhabditis elegans Male. jisc.ac.uk (PhD thesis). University of Cambridge. OCLC 500473570. EThOS uk.bl.ethos.459309.
- ^ Hodgkin, Jonathan (2004). "Jonathan Hodgkin". Current Biology. 14 (7): R259–60. doi: 10.1016/j.cub.2004.03.015. PMID 15062112. S2CID 8464632.
- ^
a
b
c
d
e
f
g
h
i Anon (1990).
"Professor Jonathan Hodgkin FRS". royalsociety.org. London:
Royal Society. Archived from
the original on 2015-11-17. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
“All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License.” -- Royal Society Terms, conditions and policies at the Wayback Machine (archived 2016-11-11)
- ^ "Jonathan Hodgkin: Former Member in Developmental Molecular Mechanisms". f1000.com. F1000. Retrieved 2012-02-14.
- ^ "Jonathan Hodgkin awarded the 2017 Novitski Prize". genestogenomes.org. 21 March 2017. Retrieved 16 April 2019.
This article incorporates
text available under the
CC BY 4.0 license.
| International | |
|---|---|
| National | |
| Academics | |