From Wikipedia, the free encyclopedia
isomaltulose synthase
Identifiers
EC no. 5.4.99.11
CAS no. 159940-49-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, an isomaltulose synthase ( EC 5.4.99.11) is an enzyme that catalyzes the chemical reaction

sucrose 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose

Hence, this enzyme has one substrate, sucrose (table sugar), and one product, 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose (also known as isomaltulose or Palatinose). It converts the α-1,2 glycosidic linkage between glucose and fructose in sucrose into the α-1,6 glycosidic linkage between glucose and fructose in isomaltulose.

This enzyme belongs to the family of isomerases. The systematic name of this enzyme class is sucrose glucosylmutase. Other names in common use include sucrose isomerase, sucrose alpha-glucosyltransferase, and trehalulose synthase.

The isomaltulose synthase of the bacterium Protaminobacter rubrum is commonly used in the industrial production of isomaltulose. [1]

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1M53, 1ZJA, 1ZJB, 2PWD, 2PWE, 2PWF, and 2PWG.

References

  1. ^ Ravaud, Stéphanie; Watzlawick, Hildegard; Haser, Richard; Mattes, Ralf; Aghajari, Nushin (2006-01-01). "Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA". Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62 (Pt 1): 74–76. PMC  2150920. PMID  16511267.


From Wikipedia, the free encyclopedia
isomaltulose synthase
Identifiers
EC no. 5.4.99.11
CAS no. 159940-49-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, an isomaltulose synthase ( EC 5.4.99.11) is an enzyme that catalyzes the chemical reaction

sucrose 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose

Hence, this enzyme has one substrate, sucrose (table sugar), and one product, 6-O-Alpha-D-Glucopyranosyl-D-Fructofuranose (also known as isomaltulose or Palatinose). It converts the α-1,2 glycosidic linkage between glucose and fructose in sucrose into the α-1,6 glycosidic linkage between glucose and fructose in isomaltulose.

This enzyme belongs to the family of isomerases. The systematic name of this enzyme class is sucrose glucosylmutase. Other names in common use include sucrose isomerase, sucrose alpha-glucosyltransferase, and trehalulose synthase.

The isomaltulose synthase of the bacterium Protaminobacter rubrum is commonly used in the industrial production of isomaltulose. [1]

Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1M53, 1ZJA, 1ZJB, 2PWD, 2PWE, 2PWF, and 2PWG.

References

  1. ^ Ravaud, Stéphanie; Watzlawick, Hildegard; Haser, Richard; Mattes, Ralf; Aghajari, Nushin (2006-01-01). "Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA". Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62 (Pt 1): 74–76. PMC  2150920. PMID  16511267.



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