Eukaryotic translation initiation factor 4B is a
protein that in humans is encoded by the EIF4Bgene.[5]
Interactions
eIF4B has been shown to
interact with and stimulate the activity of
eIF4A and bind to the
eIF3 complex through the
eIF3A subunit.[6] This interaction results in the recruitment of the
eukaryotic small ribosomal subunit (40S) to the mRNA which will in turn set the stage for the later steps leading to
elongation.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4.
doi:
10.1016/0378-1119(94)90802-8.
PMID8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56.
doi:
10.1016/S0378-1119(97)00411-3.
PMID9373149.
Eukaryotic translation initiation factor 4B is a
protein that in humans is encoded by the EIF4Bgene.[5]
Interactions
eIF4B has been shown to
interact with and stimulate the activity of
eIF4A and bind to the
eIF3 complex through the
eIF3A subunit.[6] This interaction results in the recruitment of the
eukaryotic small ribosomal subunit (40S) to the mRNA which will in turn set the stage for the later steps leading to
elongation.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4.
doi:
10.1016/0378-1119(94)90802-8.
PMID8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56.
doi:
10.1016/S0378-1119(97)00411-3.
PMID9373149.