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Names | |
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IUPAC name
3-(furan-2-carbonyl)quinoline-2-carbaldehyde
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Other names
FQ, (3-(2-furoyl)-quinoline-2 carboxaldehyde), ATTO-TAG FQ, FQCA
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Identifiers | |
3D model (
JSmol)
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ChemSpider | |
EC Number |
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PubChem
CID
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CompTox Dashboard (
EPA)
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Properties | |
C15H9NO3 | |
Molar mass | 251.241 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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3-(2-Furoyl)-quinoline-2-carboxaldehyde (FQ) is a fluorogenic amine labeling dye that is not fluorescent itself, but reacts with primary amines to form fluorescent products. [1] It was first reported in 1990. [2] Cyanide, typically provided via KCN or NaCN salts, is a required co-substrate in the fluorogenic reaction. [3] It has been used for the detection of amines and peptides, largely in CE-SDS, where it is recognized to reach a silver stain-like high sensitivity via laser-induced fluorescence. [4] Once bound to protein the excitation wavelength is 480 nm (blue) and the emission wavelength is ~600 nm (orange). [5]
![]() | |
Names | |
---|---|
IUPAC name
3-(furan-2-carbonyl)quinoline-2-carbaldehyde
| |
Other names
FQ, (3-(2-furoyl)-quinoline-2 carboxaldehyde), ATTO-TAG FQ, FQCA
| |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
EC Number |
|
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C15H9NO3 | |
Molar mass | 251.241 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
3-(2-Furoyl)-quinoline-2-carboxaldehyde (FQ) is a fluorogenic amine labeling dye that is not fluorescent itself, but reacts with primary amines to form fluorescent products. [1] It was first reported in 1990. [2] Cyanide, typically provided via KCN or NaCN salts, is a required co-substrate in the fluorogenic reaction. [3] It has been used for the detection of amines and peptides, largely in CE-SDS, where it is recognized to reach a silver stain-like high sensitivity via laser-induced fluorescence. [4] Once bound to protein the excitation wavelength is 480 nm (blue) and the emission wavelength is ~600 nm (orange). [5]