![]() | |
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.020.139 |
Chemical and physical data | |
Formula | C43H52N4O5 |
Molar mass | 704.912 g·mol−1 |
3D model ( JSmol) | |
| |
| |
![]() ![]() |
Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including Voacanga africana and Tabernaemontana divaricata. It is approved for use as an antimalarial drug in several African countries. [1] Voacamine exhibits cannabinoid CB1 receptor antagonistic activity. [2]
There is considerable confusion about the absolute stereochemical configuration of voacamine and the originally published absolute structure had to be later revised. [3] [4] It has an ibogaine unit joined with vobasine unit.
Voacamine can cause hypertension in high dose. [5]
![]() | |
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.020.139 |
Chemical and physical data | |
Formula | C43H52N4O5 |
Molar mass | 704.912 g·mol−1 |
3D model ( JSmol) | |
| |
| |
![]() ![]() |
Voacamine, also known under the older names voacanginine and vocamine, is a naturally occurring dimeric indole alkaloid of the secologanin type, found in a number of plants, including Voacanga africana and Tabernaemontana divaricata. It is approved for use as an antimalarial drug in several African countries. [1] Voacamine exhibits cannabinoid CB1 receptor antagonistic activity. [2]
There is considerable confusion about the absolute stereochemical configuration of voacamine and the originally published absolute structure had to be later revised. [3] [4] It has an ibogaine unit joined with vobasine unit.
Voacamine can cause hypertension in high dose. [5]