This article needs more
reliable medical references for
verification or relies too heavily on
primary sources. (November 2011) |
Vascular organ of lamina terminalis | |
---|---|
Details | |
Identifiers | |
Latin | organum vasculosum laminae terminalis |
MeSH | D066278 |
NeuroNames | 383 |
NeuroLex ID | nlx_anat_100313 |
TA98 | A14.1.08.940 |
TA2 | 5781 |
FMA | 62315 |
Anatomical terms of neuroanatomy |
The vascular organ of lamina terminalis (VOLT), organum vasculosum of the lamina terminalis (OVLT), or supraoptic crest [1] is one of the four sensory circumventricular organs of the brain, the others being the subfornical organ, the median eminence, and the area postrema in the brainstem. [2]
The OVLT, median eminence, and subfornical organ are interconnected with the mid- ventral hypothalamus, and together these three structures surround the third ventricle, a complex often called the anteroventral region of the third ventricle ("AV3V" region). [2] [3] [4] This region functions in the regulation of fluid and electrolyte balance by controlling thirst, sodium excretion, blood volume regulation, and vasopressin secretion. [3] [5]
The OVLT is one of the four sensory circumventricular organs providing information to other brain regions (others are median eminence, subfornical organ, and area postrema). [2] [6] [7]
OVLT capillaries do not have a blood–brain barrier, and so neurons in this region can respond to circulating factors present in the systemic circulation. [2] [5]
Neurons in the OVLT are osmoreceptors sensitive to the sodium content and osmotic pressure of blood. [3] Neurons of the lamina terminalis project to the supraoptic nucleus and paraventricular nucleus to regulate the activity of vasopressin-secreting neurons. [5] In a situation of lowered blood volume, secretion of renin by the kidneys results in the production of angiotensin II, which stimulates receptors in the VOLT and subfornical organ to complete a positive feedback loop. [5] [8] [9] These neurons also project to the median preoptic nucleus which is involved in controlling thirst. [2] [5] [8]
This article needs more
reliable medical references for
verification or relies too heavily on
primary sources. (November 2011) |
Vascular organ of lamina terminalis | |
---|---|
Details | |
Identifiers | |
Latin | organum vasculosum laminae terminalis |
MeSH | D066278 |
NeuroNames | 383 |
NeuroLex ID | nlx_anat_100313 |
TA98 | A14.1.08.940 |
TA2 | 5781 |
FMA | 62315 |
Anatomical terms of neuroanatomy |
The vascular organ of lamina terminalis (VOLT), organum vasculosum of the lamina terminalis (OVLT), or supraoptic crest [1] is one of the four sensory circumventricular organs of the brain, the others being the subfornical organ, the median eminence, and the area postrema in the brainstem. [2]
The OVLT, median eminence, and subfornical organ are interconnected with the mid- ventral hypothalamus, and together these three structures surround the third ventricle, a complex often called the anteroventral region of the third ventricle ("AV3V" region). [2] [3] [4] This region functions in the regulation of fluid and electrolyte balance by controlling thirst, sodium excretion, blood volume regulation, and vasopressin secretion. [3] [5]
The OVLT is one of the four sensory circumventricular organs providing information to other brain regions (others are median eminence, subfornical organ, and area postrema). [2] [6] [7]
OVLT capillaries do not have a blood–brain barrier, and so neurons in this region can respond to circulating factors present in the systemic circulation. [2] [5]
Neurons in the OVLT are osmoreceptors sensitive to the sodium content and osmotic pressure of blood. [3] Neurons of the lamina terminalis project to the supraoptic nucleus and paraventricular nucleus to regulate the activity of vasopressin-secreting neurons. [5] In a situation of lowered blood volume, secretion of renin by the kidneys results in the production of angiotensin II, which stimulates receptors in the VOLT and subfornical organ to complete a positive feedback loop. [5] [8] [9] These neurons also project to the median preoptic nucleus which is involved in controlling thirst. [2] [5] [8]