From Wikipedia, the free encyclopedia
Intralaminar nuclei of thalamus
Thalamic nuclei
Details
Part of Thalamus
Identifiers
Latinnuclei intralaminares thalami
Acronym(s)ITN
MeSH D020646
NeuroNames 317
NeuroLex ID birnlex_1530
TA98 A14.1.08.615
TA2 5685
FMA 62021
Anatomical terms of neuroanatomy

The intralaminar thalamic nuclei (ITN) are collections of neurons in the internal medullary lamina of the thalamus that are generally divided in two groups as follows: [1]

  • anterior (rostral) group
    • central medial nucleus
    • paracentral nucleus
    • central lateral nucleus
  • posterior (caudal) intralaminar group

Some sources also include a "central dorsal" nucleus.

Degeneration of this area can be associated with progressive supranuclear palsy and Parkinson's disease. [2] Additionally, infarction of the thalamic paramedian artery may result in varied features such as disorientation, confusion, hypersomnolence, deep coma, or akinetic mutism. [3] This area is also prominently affected in traumatic brain injuries. One postmortem study of patients with closed head injuries showed correlation of the involvement of these nuclei with the various degrees of disability. [4] [5]

See also

References

  1. ^ Mancall, E., Brock, D. & Gray, H. (2011). Gray's clinical neuroanatomy the anatomic basis for clinical neuroscience. Philadelphia: Elsevier/Saunders.
  2. ^ Henderson JM, Carpenter K, Cartwright H, Halliday GM (July 2000). "Loss of thalamic intralaminar nuclei in progressive supranuclear palsy and Parkinson's disease: clinical and therapeutic implications". Brain. 123 (7): 1410–21. doi: 10.1093/brain/123.7.1410. PMID  10869053.
  3. ^ Schmahmann, Jeremy D. (2003-09-21). "Vascular Syndromes of the Thalamus". Stroke. 34 (9): 2264–2278. doi: 10.1161/01.STR.0000087786.38997.9E. ISSN  0039-2499. PMID  12933968. S2CID  6347059.
  4. ^ Maxwell, William L.; MacKinnon, Mary Anne; Smith, Douglas H.; McIntosh, Tracy K.; Graham, David I. (2006). "Thalamic Nuclei After Human Blunt Head Injury". Journal of Neuropathology & Experimental Neurology. 65 (5): 478–488. doi: 10.1097/01.jnen.0000229241.28619.75. PMID  16772871. S2CID  15304046. Retrieved 2023-03-29.
  5. ^ Benarroch, Eduardo E. (2008-09-16). "The midline and intralaminar thalamic nuclei: Anatomic and functional specificity and implications in neurologic disease". Neurology. 71 (12): 944–949. doi: 10.1212/01.wnl.0000326066.57313.13. ISSN  0028-3878. PMID  18794498. S2CID  3397224.

External links


From Wikipedia, the free encyclopedia
Intralaminar nuclei of thalamus
Thalamic nuclei
Details
Part of Thalamus
Identifiers
Latinnuclei intralaminares thalami
Acronym(s)ITN
MeSH D020646
NeuroNames 317
NeuroLex ID birnlex_1530
TA98 A14.1.08.615
TA2 5685
FMA 62021
Anatomical terms of neuroanatomy

The intralaminar thalamic nuclei (ITN) are collections of neurons in the internal medullary lamina of the thalamus that are generally divided in two groups as follows: [1]

  • anterior (rostral) group
    • central medial nucleus
    • paracentral nucleus
    • central lateral nucleus
  • posterior (caudal) intralaminar group

Some sources also include a "central dorsal" nucleus.

Degeneration of this area can be associated with progressive supranuclear palsy and Parkinson's disease. [2] Additionally, infarction of the thalamic paramedian artery may result in varied features such as disorientation, confusion, hypersomnolence, deep coma, or akinetic mutism. [3] This area is also prominently affected in traumatic brain injuries. One postmortem study of patients with closed head injuries showed correlation of the involvement of these nuclei with the various degrees of disability. [4] [5]

See also

References

  1. ^ Mancall, E., Brock, D. & Gray, H. (2011). Gray's clinical neuroanatomy the anatomic basis for clinical neuroscience. Philadelphia: Elsevier/Saunders.
  2. ^ Henderson JM, Carpenter K, Cartwright H, Halliday GM (July 2000). "Loss of thalamic intralaminar nuclei in progressive supranuclear palsy and Parkinson's disease: clinical and therapeutic implications". Brain. 123 (7): 1410–21. doi: 10.1093/brain/123.7.1410. PMID  10869053.
  3. ^ Schmahmann, Jeremy D. (2003-09-21). "Vascular Syndromes of the Thalamus". Stroke. 34 (9): 2264–2278. doi: 10.1161/01.STR.0000087786.38997.9E. ISSN  0039-2499. PMID  12933968. S2CID  6347059.
  4. ^ Maxwell, William L.; MacKinnon, Mary Anne; Smith, Douglas H.; McIntosh, Tracy K.; Graham, David I. (2006). "Thalamic Nuclei After Human Blunt Head Injury". Journal of Neuropathology & Experimental Neurology. 65 (5): 478–488. doi: 10.1097/01.jnen.0000229241.28619.75. PMID  16772871. S2CID  15304046. Retrieved 2023-03-29.
  5. ^ Benarroch, Eduardo E. (2008-09-16). "The midline and intralaminar thalamic nuclei: Anatomic and functional specificity and implications in neurologic disease". Neurology. 71 (12): 944–949. doi: 10.1212/01.wnl.0000326066.57313.13. ISSN  0028-3878. PMID  18794498. S2CID  3397224.

External links



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