 | |
 | |
| Combination of | |
|---|---|
| Amlodipine | Calcium channel blocker |
| Benazepril | ACE inhibitor |
| Clinical data | |
| Trade names | Lotrel |
| AHFS/ Drugs.com | Professional Drug Facts |
| License data | |
|
Routes of administration | By mouth |
| Legal status | |
| Legal status |
|
 
(what is this?)
(verify) | |
Amlodipine/benazepril, marketed as Lotrel among others, is a medication used to treat high blood pressure. [1] It is a combination of amlodipine, a calcium channel blocker and benazepril, an angiotensin converting enzyme inhibitor. [1] It may be used if a single agent is not sufficient. [1] It is taken by mouth. [1]
Common side effects include cough, dizziness, and swelling. [1] Serious side effects may include angioedema, myocardial infarction, high blood potassium, liver problems, and low blood pressure. [1] Use in pregnancy is not recommended. [1] Amlodipine works by increasing the size of arteries while benazepril works by decreasing renin-angiotensin-aldosterone system activity. [1]
The combination was approved for medical use in the United States in 1995. [2] It is available as a generic medication. [3] A month supply in the United States has a wholesale cost of about US$4.50. [4] In 2017, it was the 160th most commonly prescribed medication in the United States, with more than three million prescriptions. [5] [6]
- ^ a b c d e f g h "Amlodipine besylate and benazepril hydrochloride- amlodipine besylate and benazepril hydrochloride capsule". DailyMed. U.S. National Library of Medicine. Archived from the original on 17 May 2020. Retrieved 10 March 2019.
- ^ Cerner Multum. "Amlodipine and benazepril Uses, Side Effects & Warnings". Drugs.com. Archived from the original on 20 August 2016. Retrieved 10 March 2019.
- ^ Bope, Edward T.; Kellerman, Rick D. (2016). Conn's Current Therapy 2017 E-Book. Elsevier Health Sciences. p. 124. ISBN 978-0-323-44335-7. Archived from the original on 2020-08-07. Retrieved 2020-07-11.
- ^ "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Archived from the original on 2019-03-06. Retrieved 3 March 2019.
- ^ "The Top 300 of 2020". ClinCalc DrugStats Database. ClinCalc LLC. Archived from the original on 18 March 2020. Retrieved 11 April 2020.
- ^ "Amlodipine Besylate; Benazepril Hydrochloride - Drug Usage Statistics". ClinCalc DrugStats Database. ClinCalc LLC. Archived from the original on 11 April 2020. Retrieved 11 April 2020.
|
| |
|
| |
| Combination of | |
|---|---|
| Amlodipine | Calcium channel blocker |
| Benazepril | ACE inhibitor |
| Clinical data | |
| Trade names | Lotrel |
| AHFS/ Drugs.com | Professional Drug Facts |
| License data | |
|
Routes of administration | By mouth |
| Legal status | |
| Legal status |
|
|
(what is this?)
(verify) | |
Amlodipine/benazepril, marketed as Lotrel among others, is a medication used to treat high blood pressure. [1] It is a combination of amlodipine, a calcium channel blocker and benazepril, an angiotensin converting enzyme inhibitor. [1] It may be used if a single agent is not sufficient. [1] It is taken by mouth. [1]
Common side effects include cough, dizziness, and swelling. [1] Serious side effects may include angioedema, myocardial infarction, high blood potassium, liver problems, and low blood pressure. [1] Use in pregnancy is not recommended. [1] Amlodipine works by increasing the size of arteries while benazepril works by decreasing renin-angiotensin-aldosterone system activity. [1]
The combination was approved for medical use in the United States in 1995. [2] It is available as a generic medication. [3] A month supply in the United States has a wholesale cost of about US$4.50. [4] In 2017, it was the 160th most commonly prescribed medication in the United States, with more than three million prescriptions. [5] [6]
- ^ a b c d e f g h "Amlodipine besylate and benazepril hydrochloride- amlodipine besylate and benazepril hydrochloride capsule". DailyMed. U.S. National Library of Medicine. Archived from the original on 17 May 2020. Retrieved 10 March 2019.
- ^ Cerner Multum. "Amlodipine and benazepril Uses, Side Effects & Warnings". Drugs.com. Archived from the original on 20 August 2016. Retrieved 10 March 2019.
- ^ Bope, Edward T.; Kellerman, Rick D. (2016). Conn's Current Therapy 2017 E-Book. Elsevier Health Sciences. p. 124. ISBN 978-0-323-44335-7. Archived from the original on 2020-08-07. Retrieved 2020-07-11.
- ^ "NADAC as of 2019-02-27". Centers for Medicare and Medicaid Services. Archived from the original on 2019-03-06. Retrieved 3 March 2019.
- ^ "The Top 300 of 2020". ClinCalc DrugStats Database. ClinCalc LLC. Archived from the original on 18 March 2020. Retrieved 11 April 2020.
- ^ "Amlodipine Besylate; Benazepril Hydrochloride - Drug Usage Statistics". ClinCalc DrugStats Database. ClinCalc LLC. Archived from the original on 11 April 2020. Retrieved 11 April 2020.