This article is rated B-class on Wikipedia's content assessment scale. It is of interest to the following WikiProjects:

Chemicals Mid‑importance This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals articles Mid This article has been rated as Mid-importance on the project's importance scale. Pharmacology Mid‑importance This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles Mid This article has been rated as Mid-importance on the project's importance scale. Medicine: Psychiatry Mid‑importance This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles Mid This article has been rated as Mid-importance on the project's importance scale. This article is supported by the Psychiatry task force (assessed as Mid-importance). Neuroscience Low‑importance This article is within the scope of WikiProject Neuroscience, a collaborative effort to improve the coverage of Neuroscience on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.NeuroscienceWikipedia:WikiProject NeuroscienceTemplate:WikiProject Neuroscienceneuroscience articles Low This article has been rated as Low-importance on the project's importance scale. Autism Low‑importance This article is within the scope of WikiProject Autism, a collaborative effort to improve the coverage of all aspects of autism and autistic culture on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.AutismWikipedia:WikiProject AutismTemplate:WikiProject AutismAutism articles Low This article has been rated as Low-importance on the project's importance scale. Disability Dextroamphetamine is within the scope of WikiProject Disability. For more information, visit the project page, where you can join the project and/or contribute to the discussion.DisabilityWikipedia:WikiProject DisabilityTemplate:WikiProject DisabilityDisability articles

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Dextroamphetamine. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC

Revisions succeeding this version of this article is substantially duplicated by a piece in an external publication. Please do not flag this article as a copyright violation of the following source: Amphetamines: Potent Recreational Drug of Abuse (PDF), Journal of Addiction Research & Therapy, 21 July 2017 Additional comments At least half of this "review article" is composed of copy/pasted article text with superficial revision, tables (2 total), and diagrams (2 total) from Amphetamine and Adderall#Mechanism of action without attribution to these articles.

The article currently uses the name 'dexamfetamine' intermittently as a synonym. Presumably this is an Americanism, but it's nonstandard usage and clashes with the rest of the article. I'm not even sure this is an AE/BE issue, more a case of editors using local terminology without thinking. -- Ef80 ( talk) 01:43, 8 March 2015 (UTC) reply

 Fixed - should be consistent now. Dextroamphetamine is the United States Adopted Name, while dexamfetamine is the British Approved Name, so it actually does reflect American vs British nomenclature for the drug. Seppi333 ( Insert 2¢ |  Maintained) 03:51, 8 March 2015 (UTC) reply

Interesting! I'm British and haven't encountered dexamfetamine, but then I'm not a pharmacist. Traditionally American drug nomenclature favoured 'f' and British 'ph', hence my misguess. Thanks for sorting it out. -- Ef80 ( talk) 18:42, 18 March 2015 (UTC) reply

In the edit summary Seppi said, "this needs to be cited before it's decensored."

Why does it need to be cited before it's decensored? Most of this is already noted in the several amphetamine articles. For remaining concerns a citation needed tag exists.

I can and have added some citations regarding when agents were approved or discontinued, and current status. I cannot say when Benzedrine was discontinued except that a published article in 1976 which touted Dexedrine as superior caused sales to collapse. SKF didn't use "XR" but used "spansule" which is a registered trademark. Rights to "spansule" were obviously transferred to Amedra. If you explore my FDA citations, pay attention to the application numbers to distinguish between IR and XR forms.

My original intent was to signify Vyvanse and Dyanavel are not available as generics. I saw no need to cite patent information.

Seppi also said, "It probably shouldn't be in a note due to its length."

from WP:SRF ...notes are used to add explanations, comments or other additional information relating to the main content. One of the reasons they may be used is to avoid making the text too long or awkward to read.

Making individual notes or even citation numbers would disturb the look and feel of the table. This was better handled by a single note at the title. The table makes bad inferences. Dexedrine is not available, the time release form of Dexedrine, called Spansules is available. Dexedrine was available in 1937, Dexedrine Spansules in 1976. If Spansules is cut some note is in order. Unless I missed something, Shire discontinued Adderall tablets. Correction: I was mistaken and am removing the Adderall IR discontinued part.

I'm reverting, well manually reverting with citations. I agree that notes typically should be shorter. But notes of various lengths occur and for reasons above this seems reasonable. I hate censorship. Let's try and find a solution instead. (Weren't you taking a hiatus!) — Box73 ( talk) 05:35, 30 December 2015 (UTC) Correction above — Box73 ( talk) 09:30, 30 December 2015 (UTC) reply

Thanks, looks good now. I don't particularly care that much about it being in a note, although I find it odd to have a full paragraph inside one. My only real concern was the text was uncited. Anyway, I didn't mean to suggest I wouldn't be editing at all over the holidays, merely less active and less likely to promptly respond on WP unless I get an email notice. Seppi333 ( Insert 2¢) 18:21, 30 December 2015 (UTC) reply

It has come to my attention that the chemical structure of Dextroamphetamine in this article differs from the structure presented by PubChem under the U.S National Institute of Health Website;
The amine is linked with the wedge bond as opposed to the methyl being linked with the wedge bond as presented in this article. I was hoping the community could verify the structure in this article as I'm afraid my knowledge is too limited to do so.
Linked is the official dextroamphetamine page from the Open Chemistry Database (PubChem)
Cheers,
Nukjo ( talk) 17:32, 22 June 2016 (UTC) reply

Hello fellow Wikipedians,

I have just modified 3 external links on Dextroamphetamine. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Corrected formatting/usage for http://www.af.mil/news/story.asp?id=123007615
• Added archive https://web.archive.org/web/20130505045845/http://www0.health.nsw.gov.au/PublicHealth/Pharmaceutical/adhd/faqs.asp to http://www0.health.nsw.gov.au/PublicHealth/Pharmaceutical/adhd/faqs.asp
• Added archive https://web.archive.org/web/20130518094535/http://www.ipnsm.hscni.net/news/RedAmberNewsNov10.pdf to http://www.ipnsm.hscni.net/news/RedAmberNewsNov10.pdf

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{ source check}} (last update: 18 January 2022).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.— InternetArchiveBot ( Report bug) 20:50, 9 September 2017 (UTC) reply

Hello fellow Wikipedians,

I have just modified 3 external links on Dextroamphetamine. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Added archive https://web.archive.org/web/20091219120223/http://www.medic8.com/medicines/Dexedrine.html to http://www.medic8.com/medicines/Dexedrine.html
• Added archive https://web.archive.org/web/20110617013326/http://www.dexedrine.net/faq.asp to http://www.dexedrine.net/faq.asp
• Added archive https://web.archive.org/web/20030217042723/http://www.dexedrine.net/ to http://dexedrine.net/

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{ source check}} (last update: 18 January 2022).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.— InternetArchiveBot ( Report bug) 16:03, 11 December 2017 (UTC) reply

I’ve just submitted an edit, but I thought it was worth bringing up here. I changed the captions of the first two images in this section (of the generic dextroamphetamine tablets, and the Dexedrine Spansules) to more accurately reflect the images. Note that in my edit summary I mistakenly refer to the captions as descriptions, apologies. I’m still new to this, and I’m not entirely certain of a few parts -

- Whether the first image’s caption should include “sulfate” after “Dextroamphetamine” or not, so I left it out of this edit. Also unsure if there can/should be any further clarification made for the first image’s caption, in that the bottles pictured use an alternate spelling of dextroamphetamine, “dexamphetamine” (and if required, of sulfate, “sulphate”), both of which are slightly different from the spellings used throughout the article including my current edit.

- Whether the extra information regarding the sustained-release dosage form, that I appended to the second image’s caption, is perhaps slightly excessive or could be better worded.

I’d appreciate if anybody could reply in the case of my edit needing further alteration, especially if they make such changes themselves, just for the sake of me learning a bit.

As a side note - I haven’t found any solid info to confirm this yet, but the particular medication bottles pictured in the first image are of a generic dextroamphetamine whose label states Sigma Pharmaceuticals, who presumably distributed the medication. I am fairly sure this generic form is no longer distributed in Australia by this company, but rather by Aspen Healthcare/Pharma. I actually happen to be prescribed this exact form of the medication myself (in Australia also), and the bottles I receive from pharmacies when filling the prescription have a very similar label design to the one pictured, except for saying “Aspen Pharma” as the distributor, and having the formatting slightly different. The tablets themselves also have a very slightly different shape. If I do find out it is the case that Aspen’s version has replaced Sigma’s and therefore made the latter obsolete, I’ll make another post here, and can easily update the image with a photo of my own for the sake of being contemporary. Hkstrydr ( talk) 16:16, 31 August 2020 (UTC) reply

Reviews of clinical stimulant research have established the safety and effectiveness of long-term continuous amphetamine use for the treatment of ADHD.[27][28][29]

The article in reference 27 does not specifically concern dextroamphetamine but studies more methylphenidate, atomoxetine, guanfacine, imipramine/desipramine, clonidine, bupropion and tricyclic antidepressants. By using "general" information on ADHD-medication, it is giving some assumptions regarding the product dextroamphetamine when this might not correspond to reality ! I did not check references 28 nor 29 but suggest that these are checked too and the paragraph be reviewed in order to include only information relevant to dexamphetamine. — Preceding unsigned comment added by 85.127.144.170 ( talk) 14:04, 25 September 2020 (UTC) reply

I hope not to bore everyone over a small detail in an otherwise very appealing article, but I've noticed a rather annoying error at reference 69 or so. It probably originates from a transclusion from the "Amphetamine article", and has been there for a while... I've spent an embarrassing amount of time trying to remove, but Satan clearly jammed that thing good. How would you suggest fixing it? Horsesizedduck ( talk) 21:34, 27 June 2021 (UTC) reply

Doses above 60mg daily considered harmful? 66.135.148.160 ( talk) 08:46, 12 January 2022 (UTC) reply

WRT to the following:

" It also shares many chemical and pharmacological properties with human trace amines, particularly phenethylamine and N-methylphenethylamine, the latter being an isomer of amphetamine produced within the human body."

The final phrase might suggestion to some that N-methylphenethylamine functions like amphetamine, but merely being isomers does not point to a structure-function relationship, plus there is no reference so I think the text starting with "the latter..." should be deleted.

Spope3 ( talk) 23:46, 25 May 2022 (UTC) reply