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I am pretty sure scenes were filmed at the old Parke, Davis and Co. pharmaceutical manufacturing compound around Joseph Campau, McDougall, and the Detroit River in downtown Detroit. Many of the buildings were constructed in the late 1800s and early 1900s, and are still erect in 2016, although re-purposed. Drug development & manufacturing ceased in 1981, as activities were dispatched to newer facilities in Morris Plains, NJ, Rochester, MI, Lititz, PA, Greenwood, SC, and Ann Arbor, MI. — Preceding unsigned comment added by 216.115.238.102 ( talk) 08:30, 17 April 2016 (UTC) reply