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Onychomycosis article. This is not a forum for general discussion of the article's subject. |
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Onchomycosis can be caused by many different fungi, and many other conditions like a psoriatic nail and paronychia can look so much like it that dermatologists still need to have a lab workup done. What was the causal agent, if any, of the wife's onychomycosis that was relieved with vinegar? How can anyone possibly give universal medical advice based on one person's kitchen experiments with the application of 19th century hygiene principles to an (I strongly suspect) undiagnosed condition?
Mercurochrome contains mercury and is banned in the US. All sorts of these common home disinfectants were tested against fungal skin and nail infections in the 1910's to 1950's and the only one that stood out as somewhat effective was Whitfield's ointment, with the active ingredient benzoic acid. But even it doesn't stand up to scientific comparison as a serious onychomycosis remedy. The common fungi causing dermatophyte onychomycosis are too deeply seated in the nail to be affected by materials applied to the surface (unless the materials are combined with chemical nail softeners under occlusion). Mercurochrome is commonly used in developing countries to treat fungal ear canal infestation (otomycosis), but there the fungus is right at the surface. Mercurochrome can't even penetrate to kill the endospores within spore-forming bacteria.
Onychomycosis isn't life-threatening but casual treatment recommendations based on anecdotes are no more helpful here than they are in any other disease. No doubt carrot juice and staying optimistic cured somebody's wife's cancer somewhere, but there's a serious ethical problem with extending this observation into a general prescription. Yes, any individual could make a novel observation -- but there's nothing novel about applying vinegar, iodine, garlic, lemon peel, oregano, etc. against fungal skin infections. It's been done. Tea tree oil is still being investigated but results are mixed (for references go to Entrez PubMed website and search on keywords: tea tree oil onychomycosis. Also: tea tree oil tinea. Also: tea tree oil dermatophyte). Keywords for the otomycosis statement above are otomycosis mercurochrome.
Summerbell 18:32, 26 September 2006 (UTC)
Still, a personal experience is not fitting in an article like this, such anecdotes can be piled on one another in a bulletin board thread. A wiki article should provide an overview and description of the topic and that information should be somewhat objective. "there is some anecdotal evidence that suggests the ability of creme fraiche to cure nail fungus (not being funny here, there really is), however, no scientific investigation have been performed and whether the substance can be effective is unknown." is an OK entry, as it is unbiased and not misleading. "creme fraiche did it for me!" is not a good entry because a personal anecdote does not have a place in a medical article, and especially not without a specified source. — Preceding unsigned comment added by Gaffa11 ( talk • contribs) 08:28, 15 June 2011 (UTC)
I could get one. The question is, would anyone really want to see it?
My wife had an infection and cured it by soaking the infected toe for 30 minutes in vinegar every day for 3 months. She would keep the nail as trimmed as possible the whole time. Don't cause your body stress with something like Lamisil. Save your money and health.
I wanted to add something on the FDA OTC Topical Antifungal Monograph, but all I could find were some very general bits of info on the FDA website (see [1] and [2]). I also haven't been able to find anything on the FDA's 1994 ruling that said that no OTC anti-fungal product was effective on nails, and required the wording "this product is not effective on scalp or nails" on all OTC anti-fungal products (even if they were still allowed to use trademarks such as Fungi-Nail!). The closest I could find was this DOC file Comparison of Labeling for All Topical Antifungals Treating Athlete’s Foot. Can anyone provide better information? Blank Verse 15:37, 29 August 2006 (UTC)
The article that is referenced does not say that tea-tree oil doesn't work because the fungus is too deep subsurface. This needs more evidence or is WP:OR. Pgr94 18:41, 13 June 2007 (UTC)
References
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link)
The section related to tea tree oil was removed from the 'natural remedies' section via this edit by User:68.36.170.182. Was this removal in accordance with consensus? --User:Ceyockey ( talk to me) 01:12, 1 July 2007 (UTC)
Here is a summary of this topic from a 2002 article in the Journal of Antimicrobial Chemotherapy [3]:
Based on both its inhibitory and fungicidal action, tea tree oil may be a useful agent for treating dermatophyte infections. However, exactly how this in vitro activity translates into in vivo effectiveness is unclear.
[... summary of two clinical trials ...]
Given that onychomycosis rarely responds to topical therapy and is therefore usually treated systemically,20 it is perhaps not surprising that the topical application of tea tree oil was of limited effectiveness in these two clinical trials. This emphasizes the need for more clinical trial data, particularly in relation to tinea pedis, which can often be treated successfully topically.20
So it seems there is little-to-no evidence to support the claim either way. Furthermore, given topical treatments don't really work for onychomycosis, there are grounds for believing tea-tree oil won't work either. Pgr94 19:02, 9 October 2007 (UTC)
This statement remains in the other section, despite some inconsistency with the reference quoted:
Tea tree oil is not recommended as a treatment, since it is not effective and can irritate the surrounding skin. [4]
The reference does review some studies suggesting that tea tree oil is ineffective, but also mentions one showing 80% effectiveness:
Another study was a double-blind, placebo-controlled trial involving 60 patients with clinical and mycologic evidence of DLSO who were randomized to treatment with a cream containing butenafine hydrochloride 2% and TTO 5% (n=40) or a control cream containing only TTO (n=20), with active treatment for 8 weeks and final follow-up at 36 weeks.30 Patients were instructed to apply the cream 3 times daily under occlusion for 8 weeks and the nail was debrided between weeks 4 and 6 if feasible. If the nail could not be debrided after 8 weeks, it was considered resistant to treatment. At the end of the study, the complete cure rate was 80% in the active group compared to 0% in the placebo group (P<.0001), and the mean time to complete healing with progressive nail growth was 29 weeks. There were no adverse effects in the placebo group, but 4 patients in the active group had mild skin inflammation.
This completely unverifiable: the only sources discussing Crocodile Oil are those selling it, usually trying to blind with pseudo-science. For more on this see the discussion for Crocodile Oil Almost-instinct ( talk) 22:46, 19 April 2008 (UTC)
There are different types of onychomycosis. It would be good to get images of each type. For example see [5] Pgr94 10:25, 18 September 2007 (UTC)
different types of onychomysosis will look mostly the same, be somewhat misleading (as for the most part, this is not a tool used to dignose the type of fungus... and may be somewhat trivial to categorize. Certainly additional photos of a general nature are always of value. —Preceding unsigned comment added by Spamwatch ( talk • contribs) 18:59, 13 November 2007 (UTC)
As no evidence has been found for vinegar since Feb. 2007, I have removed it.
Distilled white vinegar. citation needed Drops are applied to the cuticle twice a day. This method does not kill the fungus, but the vinegar allegedly changes the pH (acid content) of the new nail formed in that 12-hour period. (The scientific perspective, however, is that vinegar is unlikely to penetrate the dense keratinous tissue thoroughly enough to have any significant effect. Instead, it may be absorbed by the skin above the nail and work its way to where the nail is actually forming.) As the old, infected nail grows and is cut away, it is said to be replaced by an acidic nail, uninhabitable by fungi. Several months of consistent application are involved.
Pgr94 ( talk) 13:14, 29 November 2007 (UTC)
I went to a podiatrist who told me to soak my foot in white vinegar for three months but I won’t see the results for one year. June 1 2009. —Preceding unsigned comment added by 75.45.16.130 ( talk) 01:37, 13 May 2009 (UTC)
If someone with access to good sources could examine these issues and possibly amend the article it would be appreciated
Thanks, Wanderer57 ( talk) 20:33, 30 March 2008 (UTC)
It depends. The first stage is usually infection of the tip of the nail and the nail bed. As the fungus works its way back the entire nail and nail bed can be infected, and eventually it can reach the nail matrix. I have no really good link at the moment but check http://www.patient.info/doctor/Fungal-Nail-Infections.htm .
You are right about the penetration problem. Drilling holes may or may not be helpful, I have tried it with a .25 mm drill and applied various topical substances but the small holes tend to clog up quickly and probably only a little of the topical agents get through. To my knowledge no research is being done on this type of approach to drug transport into the nail. — Preceding unsigned comment added by Gaffa11 ( talk • contribs) 08:45, 15 June 2011 (UTC)
Short of time right now so this a note to self, or anyone who else wants to follow recents developments.
pgr94 ( talk) 22:25, 20 October 2008 (UTC)
I've had severe toenail fungus for just over forty years. It started when I lived in the tropics.
At this writing, the fungus is completely expelled in two nails, is almost done being expelled in four others, and halfway gone in the big toes. Two were already clear.
How? I soak the toes in 50% Listerine, 50% white vinegar, for 30-45 minutes every night. I started about four months ago. I didn't make this up - a Google search for "Listerine toenail fungus" finds many testimonials, and occasional discussions of the method of operation. It seems that the fungi can't handle eucalyptol and thymol, plus the other assorted toxins that make Listerine lethal when a lot is swallowed.
Not sure if a photo of the half-clear big toes would be helpful. —Preceding unsigned comment added by MoonDJ ( talk • contribs) 16:33, 31 July 2010 (UTC)
On recommendation from my GP, using a cotton swab, applying a single drop of undiluted bleach twice a day underneath my toenail is rapidly removing the fungus. Half of the nail bed has recovered in 6 months. Application is quick and there seems to be no tissue damage. If considered, use caution though... RudiBosbouer ( talk) 08:03, 14 January 2011 (UTC)
These should be used as refs rather than as further reading
Doc James ( talk · contribs · email) 17:00, 26 May 2011 (UTC)
I was diagnosed with Onychomycosis and was treated with fulvacin. The condition was eliminated within 45 days as the nail grew out. Any claim of a "challenging" treatment in this article seems to exist in order to appease believers in alternative and holistic remedies, or to appease persons apprehensive of "mainstream" treatments. Claims of a cure based on garlic/vinegar/lasers/prayer seems dubious at best. My chemical-laden, corporate/mainstream/liver-killing treatment cured my condition post haste, and I wouldn't have it any other way. Enjoy your fungus -- I'm sure your girl loves it!! — Preceding unsigned comment added by 69.60.103.173 ( talk) 04:51, 1 May 2012 (UTC)
Once I had an infection in one of the foot's small fingers, it lasted for at least a year, until I removed the nail myself with a tweezer. The nail grew back and the infection was gone. Any opinions from physicians or scientific studies in this regard? — Preceding unsigned comment added by 220.238.51.163 ( talk) 02:24, 3 November 2012 (UTC)
There are products on the market claiming to cure onychomycosis with Undecylenic acid as the active ingredient. Pubmed doesn't show very strong evidence for this. E.g. [6]. Does anyone know of any other evidence for undecylenic acid? Meanwhile beware that the science doesn't appear to support the claims of "Fungi Nail"'s peddlars. (www.funginail.com) Treat nail fungus infection. Suitable for everyone (all ages) Tested clinically with 100 % efficiency after 12 weeks of use. [7] pgr94 ( talk) 18:08, 20 January 2013 (UTC)
Onychomycosis is infection of the nail. Paronychia is infection around the nail. The lede of each article should make readers aware of the other, closely related article. (I have tried to cross-link the articles. My work was reverted. Now the matter is in your hands.) - 71.174.175.150 ( talk) 15:08, 2 January 2015 (UTC)
I had nail fungus back in 2000 and was prescribed Griseofulvin and it knocked it out in four months. I think this drug has been generic since the birth of Christ, so I'm not shilling for big pharma/the liver killing industry. Just saying what worked for me. You can soak your toes in bleach/vinegar/witch potion all you want. Have fun with your nail fungus. 24.51.217.118 ( talk) 22:06, 13 October 2015 (UTC)
Tea tree oil has demonstrated some benefit in the treatment of onychomycosis. [1] [2] [3] A 2012 review by the National Institutes of Health says that a "topical application of 100% tea tree oil solution, twice daily for six months, can cure fungal toenail infection in about 18% of people who try it." [4] |
-- Timeshifter ( talk) 13:48, 29 May 2016 (UTC)
References
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link). Abstract: "Tea tree oil was found to be able to inhibit growth of all clinical fungal isolates."
I am not sure about the NIH quote. I copied that reference from the tea tree oil article.
Concerning tea tree oil a 2012 review by the National Institutes of Health found some small studies on its use. [1] "Some smaller-scale clinical studies have had positive results for treating athlete's foot, nail fungus, dandruff, and acne, but more large-scale, well-designed clinical studies are needed." |
There are more scientific references in this article:
See the "What Does Science Say?" section of the article. A quote:
A randomized, controlled trial published in the Journal of Family Practice examined the effectiveness of a twice-daily application of 100% tea tree oil, compared to a 1% topical application of clotrimazole antifungal medication. After six months, the tea tree oil was found to be as effective as the topical antifungal for the 177 study participants. After about three months, half of each group reported partial or full resolution of symptoms. |
That section also discusses the tea tree oil article in the Natural Medicines Comprehensive Database. It uses a dead link though. Here is a working link:
I may not have time to edit this Wikipedia article much. But I can add some references here now and then for others to use and dissect. I find it telling that Wikipedia does not have an article yet for the Natural Medicines Comprehensive Database (link is to its "about" page). Not notable? ;) -- Timeshifter ( talk) 14:26, 30 May 2016 (UTC)
References
Concerning tea tree oil a 2012 review by the National Institutes of Health found some small studies on its use. [1] "Some smaller-scale clinical studies have had positive results for treating athlete's foot, nail fungus, dandruff, and acne, but more large-scale, well-designed clinical studies are needed." A double-blind 1994 study of 117 patients found that topical treatment with 100% tea tree oil got the same result as a 1% clotrimazole solution after 6 months of treatment, and also 3 months later after treatment. There was partial or full resolution by 60 and 61% of participants respectively after 6 months of treatment. [2] |
References
(unindent). See WP:NOTPAPER and WP:OWN. Your current summary is inadequate and inaccurate:
As of 2013 tea tree oil has failed to demonstrate benefit in the treatment of onychomycosis. [1] A 2012 review by the National Institutes of Health found some small and tentative studies on its use. [2] |
References
I put the wikipedia article quotes into boxes. Different background colors to show evolution of my suggestions versus yours. I haven't suggested another possibility yet. I want to check the review articles to see how many different 100% tea tree oil studies they are referring to. Or someone else can check.
The full text for the 2013 review you cite is found here:
-- Timeshifter ( talk) 23:10, 21 June 2016 (UTC)
- https://pubmed.ncbi.nlm.nih.gov/18484426
- https://pubmed.ncbi.nlm.nih.gov/18569273
If you have similar or other new references, please extend. KR 17387349L8764 ( talk) 18:39, 10 May 2021 (UTC)
This is the
talk page for discussing improvements to the
Onychomycosis article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL |
![]() | This ![]() It is of interest to the following WikiProjects: | |||||||||||||||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Onychomycosis.
|
Onchomycosis can be caused by many different fungi, and many other conditions like a psoriatic nail and paronychia can look so much like it that dermatologists still need to have a lab workup done. What was the causal agent, if any, of the wife's onychomycosis that was relieved with vinegar? How can anyone possibly give universal medical advice based on one person's kitchen experiments with the application of 19th century hygiene principles to an (I strongly suspect) undiagnosed condition?
Mercurochrome contains mercury and is banned in the US. All sorts of these common home disinfectants were tested against fungal skin and nail infections in the 1910's to 1950's and the only one that stood out as somewhat effective was Whitfield's ointment, with the active ingredient benzoic acid. But even it doesn't stand up to scientific comparison as a serious onychomycosis remedy. The common fungi causing dermatophyte onychomycosis are too deeply seated in the nail to be affected by materials applied to the surface (unless the materials are combined with chemical nail softeners under occlusion). Mercurochrome is commonly used in developing countries to treat fungal ear canal infestation (otomycosis), but there the fungus is right at the surface. Mercurochrome can't even penetrate to kill the endospores within spore-forming bacteria.
Onychomycosis isn't life-threatening but casual treatment recommendations based on anecdotes are no more helpful here than they are in any other disease. No doubt carrot juice and staying optimistic cured somebody's wife's cancer somewhere, but there's a serious ethical problem with extending this observation into a general prescription. Yes, any individual could make a novel observation -- but there's nothing novel about applying vinegar, iodine, garlic, lemon peel, oregano, etc. against fungal skin infections. It's been done. Tea tree oil is still being investigated but results are mixed (for references go to Entrez PubMed website and search on keywords: tea tree oil onychomycosis. Also: tea tree oil tinea. Also: tea tree oil dermatophyte). Keywords for the otomycosis statement above are otomycosis mercurochrome.
Summerbell 18:32, 26 September 2006 (UTC)
Still, a personal experience is not fitting in an article like this, such anecdotes can be piled on one another in a bulletin board thread. A wiki article should provide an overview and description of the topic and that information should be somewhat objective. "there is some anecdotal evidence that suggests the ability of creme fraiche to cure nail fungus (not being funny here, there really is), however, no scientific investigation have been performed and whether the substance can be effective is unknown." is an OK entry, as it is unbiased and not misleading. "creme fraiche did it for me!" is not a good entry because a personal anecdote does not have a place in a medical article, and especially not without a specified source. — Preceding unsigned comment added by Gaffa11 ( talk • contribs) 08:28, 15 June 2011 (UTC)
I could get one. The question is, would anyone really want to see it?
My wife had an infection and cured it by soaking the infected toe for 30 minutes in vinegar every day for 3 months. She would keep the nail as trimmed as possible the whole time. Don't cause your body stress with something like Lamisil. Save your money and health.
I wanted to add something on the FDA OTC Topical Antifungal Monograph, but all I could find were some very general bits of info on the FDA website (see [1] and [2]). I also haven't been able to find anything on the FDA's 1994 ruling that said that no OTC anti-fungal product was effective on nails, and required the wording "this product is not effective on scalp or nails" on all OTC anti-fungal products (even if they were still allowed to use trademarks such as Fungi-Nail!). The closest I could find was this DOC file Comparison of Labeling for All Topical Antifungals Treating Athlete’s Foot. Can anyone provide better information? Blank Verse 15:37, 29 August 2006 (UTC)
The article that is referenced does not say that tea-tree oil doesn't work because the fungus is too deep subsurface. This needs more evidence or is WP:OR. Pgr94 18:41, 13 June 2007 (UTC)
References
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link)
The section related to tea tree oil was removed from the 'natural remedies' section via this edit by User:68.36.170.182. Was this removal in accordance with consensus? --User:Ceyockey ( talk to me) 01:12, 1 July 2007 (UTC)
Here is a summary of this topic from a 2002 article in the Journal of Antimicrobial Chemotherapy [3]:
Based on both its inhibitory and fungicidal action, tea tree oil may be a useful agent for treating dermatophyte infections. However, exactly how this in vitro activity translates into in vivo effectiveness is unclear.
[... summary of two clinical trials ...]
Given that onychomycosis rarely responds to topical therapy and is therefore usually treated systemically,20 it is perhaps not surprising that the topical application of tea tree oil was of limited effectiveness in these two clinical trials. This emphasizes the need for more clinical trial data, particularly in relation to tinea pedis, which can often be treated successfully topically.20
So it seems there is little-to-no evidence to support the claim either way. Furthermore, given topical treatments don't really work for onychomycosis, there are grounds for believing tea-tree oil won't work either. Pgr94 19:02, 9 October 2007 (UTC)
This statement remains in the other section, despite some inconsistency with the reference quoted:
Tea tree oil is not recommended as a treatment, since it is not effective and can irritate the surrounding skin. [4]
The reference does review some studies suggesting that tea tree oil is ineffective, but also mentions one showing 80% effectiveness:
Another study was a double-blind, placebo-controlled trial involving 60 patients with clinical and mycologic evidence of DLSO who were randomized to treatment with a cream containing butenafine hydrochloride 2% and TTO 5% (n=40) or a control cream containing only TTO (n=20), with active treatment for 8 weeks and final follow-up at 36 weeks.30 Patients were instructed to apply the cream 3 times daily under occlusion for 8 weeks and the nail was debrided between weeks 4 and 6 if feasible. If the nail could not be debrided after 8 weeks, it was considered resistant to treatment. At the end of the study, the complete cure rate was 80% in the active group compared to 0% in the placebo group (P<.0001), and the mean time to complete healing with progressive nail growth was 29 weeks. There were no adverse effects in the placebo group, but 4 patients in the active group had mild skin inflammation.
This completely unverifiable: the only sources discussing Crocodile Oil are those selling it, usually trying to blind with pseudo-science. For more on this see the discussion for Crocodile Oil Almost-instinct ( talk) 22:46, 19 April 2008 (UTC)
There are different types of onychomycosis. It would be good to get images of each type. For example see [5] Pgr94 10:25, 18 September 2007 (UTC)
different types of onychomysosis will look mostly the same, be somewhat misleading (as for the most part, this is not a tool used to dignose the type of fungus... and may be somewhat trivial to categorize. Certainly additional photos of a general nature are always of value. —Preceding unsigned comment added by Spamwatch ( talk • contribs) 18:59, 13 November 2007 (UTC)
As no evidence has been found for vinegar since Feb. 2007, I have removed it.
Distilled white vinegar. citation needed Drops are applied to the cuticle twice a day. This method does not kill the fungus, but the vinegar allegedly changes the pH (acid content) of the new nail formed in that 12-hour period. (The scientific perspective, however, is that vinegar is unlikely to penetrate the dense keratinous tissue thoroughly enough to have any significant effect. Instead, it may be absorbed by the skin above the nail and work its way to where the nail is actually forming.) As the old, infected nail grows and is cut away, it is said to be replaced by an acidic nail, uninhabitable by fungi. Several months of consistent application are involved.
Pgr94 ( talk) 13:14, 29 November 2007 (UTC)
I went to a podiatrist who told me to soak my foot in white vinegar for three months but I won’t see the results for one year. June 1 2009. —Preceding unsigned comment added by 75.45.16.130 ( talk) 01:37, 13 May 2009 (UTC)
If someone with access to good sources could examine these issues and possibly amend the article it would be appreciated
Thanks, Wanderer57 ( talk) 20:33, 30 March 2008 (UTC)
It depends. The first stage is usually infection of the tip of the nail and the nail bed. As the fungus works its way back the entire nail and nail bed can be infected, and eventually it can reach the nail matrix. I have no really good link at the moment but check http://www.patient.info/doctor/Fungal-Nail-Infections.htm .
You are right about the penetration problem. Drilling holes may or may not be helpful, I have tried it with a .25 mm drill and applied various topical substances but the small holes tend to clog up quickly and probably only a little of the topical agents get through. To my knowledge no research is being done on this type of approach to drug transport into the nail. — Preceding unsigned comment added by Gaffa11 ( talk • contribs) 08:45, 15 June 2011 (UTC)
Short of time right now so this a note to self, or anyone who else wants to follow recents developments.
pgr94 ( talk) 22:25, 20 October 2008 (UTC)
I've had severe toenail fungus for just over forty years. It started when I lived in the tropics.
At this writing, the fungus is completely expelled in two nails, is almost done being expelled in four others, and halfway gone in the big toes. Two were already clear.
How? I soak the toes in 50% Listerine, 50% white vinegar, for 30-45 minutes every night. I started about four months ago. I didn't make this up - a Google search for "Listerine toenail fungus" finds many testimonials, and occasional discussions of the method of operation. It seems that the fungi can't handle eucalyptol and thymol, plus the other assorted toxins that make Listerine lethal when a lot is swallowed.
Not sure if a photo of the half-clear big toes would be helpful. —Preceding unsigned comment added by MoonDJ ( talk • contribs) 16:33, 31 July 2010 (UTC)
On recommendation from my GP, using a cotton swab, applying a single drop of undiluted bleach twice a day underneath my toenail is rapidly removing the fungus. Half of the nail bed has recovered in 6 months. Application is quick and there seems to be no tissue damage. If considered, use caution though... RudiBosbouer ( talk) 08:03, 14 January 2011 (UTC)
These should be used as refs rather than as further reading
Doc James ( talk · contribs · email) 17:00, 26 May 2011 (UTC)
I was diagnosed with Onychomycosis and was treated with fulvacin. The condition was eliminated within 45 days as the nail grew out. Any claim of a "challenging" treatment in this article seems to exist in order to appease believers in alternative and holistic remedies, or to appease persons apprehensive of "mainstream" treatments. Claims of a cure based on garlic/vinegar/lasers/prayer seems dubious at best. My chemical-laden, corporate/mainstream/liver-killing treatment cured my condition post haste, and I wouldn't have it any other way. Enjoy your fungus -- I'm sure your girl loves it!! — Preceding unsigned comment added by 69.60.103.173 ( talk) 04:51, 1 May 2012 (UTC)
Once I had an infection in one of the foot's small fingers, it lasted for at least a year, until I removed the nail myself with a tweezer. The nail grew back and the infection was gone. Any opinions from physicians or scientific studies in this regard? — Preceding unsigned comment added by 220.238.51.163 ( talk) 02:24, 3 November 2012 (UTC)
There are products on the market claiming to cure onychomycosis with Undecylenic acid as the active ingredient. Pubmed doesn't show very strong evidence for this. E.g. [6]. Does anyone know of any other evidence for undecylenic acid? Meanwhile beware that the science doesn't appear to support the claims of "Fungi Nail"'s peddlars. (www.funginail.com) Treat nail fungus infection. Suitable for everyone (all ages) Tested clinically with 100 % efficiency after 12 weeks of use. [7] pgr94 ( talk) 18:08, 20 January 2013 (UTC)
Onychomycosis is infection of the nail. Paronychia is infection around the nail. The lede of each article should make readers aware of the other, closely related article. (I have tried to cross-link the articles. My work was reverted. Now the matter is in your hands.) - 71.174.175.150 ( talk) 15:08, 2 January 2015 (UTC)
I had nail fungus back in 2000 and was prescribed Griseofulvin and it knocked it out in four months. I think this drug has been generic since the birth of Christ, so I'm not shilling for big pharma/the liver killing industry. Just saying what worked for me. You can soak your toes in bleach/vinegar/witch potion all you want. Have fun with your nail fungus. 24.51.217.118 ( talk) 22:06, 13 October 2015 (UTC)
Tea tree oil has demonstrated some benefit in the treatment of onychomycosis. [1] [2] [3] A 2012 review by the National Institutes of Health says that a "topical application of 100% tea tree oil solution, twice daily for six months, can cure fungal toenail infection in about 18% of people who try it." [4] |
-- Timeshifter ( talk) 13:48, 29 May 2016 (UTC)
References
{{
cite journal}}
: CS1 maint: multiple names: authors list (
link). Abstract: "Tea tree oil was found to be able to inhibit growth of all clinical fungal isolates."
I am not sure about the NIH quote. I copied that reference from the tea tree oil article.
Concerning tea tree oil a 2012 review by the National Institutes of Health found some small studies on its use. [1] "Some smaller-scale clinical studies have had positive results for treating athlete's foot, nail fungus, dandruff, and acne, but more large-scale, well-designed clinical studies are needed." |
There are more scientific references in this article:
See the "What Does Science Say?" section of the article. A quote:
A randomized, controlled trial published in the Journal of Family Practice examined the effectiveness of a twice-daily application of 100% tea tree oil, compared to a 1% topical application of clotrimazole antifungal medication. After six months, the tea tree oil was found to be as effective as the topical antifungal for the 177 study participants. After about three months, half of each group reported partial or full resolution of symptoms. |
That section also discusses the tea tree oil article in the Natural Medicines Comprehensive Database. It uses a dead link though. Here is a working link:
I may not have time to edit this Wikipedia article much. But I can add some references here now and then for others to use and dissect. I find it telling that Wikipedia does not have an article yet for the Natural Medicines Comprehensive Database (link is to its "about" page). Not notable? ;) -- Timeshifter ( talk) 14:26, 30 May 2016 (UTC)
References
Concerning tea tree oil a 2012 review by the National Institutes of Health found some small studies on its use. [1] "Some smaller-scale clinical studies have had positive results for treating athlete's foot, nail fungus, dandruff, and acne, but more large-scale, well-designed clinical studies are needed." A double-blind 1994 study of 117 patients found that topical treatment with 100% tea tree oil got the same result as a 1% clotrimazole solution after 6 months of treatment, and also 3 months later after treatment. There was partial or full resolution by 60 and 61% of participants respectively after 6 months of treatment. [2] |
References
(unindent). See WP:NOTPAPER and WP:OWN. Your current summary is inadequate and inaccurate:
As of 2013 tea tree oil has failed to demonstrate benefit in the treatment of onychomycosis. [1] A 2012 review by the National Institutes of Health found some small and tentative studies on its use. [2] |
References
I put the wikipedia article quotes into boxes. Different background colors to show evolution of my suggestions versus yours. I haven't suggested another possibility yet. I want to check the review articles to see how many different 100% tea tree oil studies they are referring to. Or someone else can check.
The full text for the 2013 review you cite is found here:
-- Timeshifter ( talk) 23:10, 21 June 2016 (UTC)
- https://pubmed.ncbi.nlm.nih.gov/18484426
- https://pubmed.ncbi.nlm.nih.gov/18569273
If you have similar or other new references, please extend. KR 17387349L8764 ( talk) 18:39, 10 May 2021 (UTC)