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Thanks to Gak for recent additions, but there is now seems a conflict in the article as to making the diagnosis and when a patient is referred to a haematologist.
Previously the article would have inferred (although not explicitly so stated) that diagnosis is purely by serum electrophoresis identifying a monoclonal band and of this being a small quantity (a high level indicating a multiple myeloma). Only with annual protein electrophoresis monitoring, showing an increasing level, would referral then be made to a haematologist and only then would they arrange an X-ray skeletal survey.
The current version of the article though implies that a skeletal survey is required as part of the original diagnosis, and thus that immediate initial referral to a haematologist is required in order to have this requested & arranged. Of the few cases that I have identified in the last few years, I seem to recall that on speaking to various local haematologists that not all cases were deemed needing referral, and of those that I did refer, not all had initial skeletal surveys performed.
Hence 2 questions:
Hi, please don't delete my table before discussing it here on the talk page...I think it's important for people to consider the differential diagnosis of MGUS, because it ain't all myeloma. I had a rash of scared patients in my office last month for monoclonal gammopathy, convinced after "research on the internet" that they had myeloma, and one turned out to have Guillain-Barre (!) and the other a Splenic Marginal Zone Lymphoma (!). So we should consider the alternatives before doctors or patients assume the worst.-- Dr.michael.benjamin 07:59, 19 February 2007 (UTC)
Is MGUS the same as "Benign Monoclonal Gammopathy"? I've updated the infobox under the assumption that it is, but if it isn't, feel free to revert my edit. -- Arcadian 14:21, 19 April 2007 (UTC)
doi: 10.1182/blood-2008-04-151076 shows that DVT risk is increased threefold. JFW | T@lk 22:55, 23 October 2008 (UTC)
This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||
|
Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Monoclonal gammopathy of undetermined significance.
|
Thanks to Gak for recent additions, but there is now seems a conflict in the article as to making the diagnosis and when a patient is referred to a haematologist.
Previously the article would have inferred (although not explicitly so stated) that diagnosis is purely by serum electrophoresis identifying a monoclonal band and of this being a small quantity (a high level indicating a multiple myeloma). Only with annual protein electrophoresis monitoring, showing an increasing level, would referral then be made to a haematologist and only then would they arrange an X-ray skeletal survey.
The current version of the article though implies that a skeletal survey is required as part of the original diagnosis, and thus that immediate initial referral to a haematologist is required in order to have this requested & arranged. Of the few cases that I have identified in the last few years, I seem to recall that on speaking to various local haematologists that not all cases were deemed needing referral, and of those that I did refer, not all had initial skeletal surveys performed.
Hence 2 questions:
Hi, please don't delete my table before discussing it here on the talk page...I think it's important for people to consider the differential diagnosis of MGUS, because it ain't all myeloma. I had a rash of scared patients in my office last month for monoclonal gammopathy, convinced after "research on the internet" that they had myeloma, and one turned out to have Guillain-Barre (!) and the other a Splenic Marginal Zone Lymphoma (!). So we should consider the alternatives before doctors or patients assume the worst.-- Dr.michael.benjamin 07:59, 19 February 2007 (UTC)
Is MGUS the same as "Benign Monoclonal Gammopathy"? I've updated the infobox under the assumption that it is, but if it isn't, feel free to revert my edit. -- Arcadian 14:21, 19 April 2007 (UTC)
doi: 10.1182/blood-2008-04-151076 shows that DVT risk is increased threefold. JFW | T@lk 22:55, 23 October 2008 (UTC)