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In the chapter titled "Incidence/prevalence" it is stated: "A less than recommended dietary intake does not necessarily imply magnesium deficiency in an individual" There is no citation to back this up and it does not make logical sense either as the RDA was set up specifically to help prevent deficiencies.
I request permission to remove this sentence.-- 197.79.0.1 ( talk) 19:14, 31 May 2013 (UTC)
Nobody here is acknowledging my edit request. I am going ahead with the edit, please do not reverse it without explaining here first.-- 197.79.8.214 ( talk) 18:52, 7 June 2013 (UTC)
On the Magnesium page, under "Biological roles",
[1] it states that "Human magnesium deficiency (including conditions that show few overt symptoms) is relatively rare" with a link to the following NIH page.
[2] There, a fair way down, under "Magnesium Deficiency",
[3] it states "Symptomatic magnesium deficiency due to low dietary intake in otherwise-healthy people is uncommon because the kidneys limit urinary excretion of this mineral" along with a footnote link to a cited source for that information. It sounds like higher intake means your body eliminates the excess, and lower intake means it hangs onto it, so you really need to have some issues before you have symptoms. That's what all the information I've seen on these pages implies. I'm sure someone with more knowledge than I have could find all the sources and put them together.
96.39.170.184 (
talk)
18:04, 1 July 2014 (UTC) C.S. Rowan
References
Very nice job on the rewriting and fleshing out, Nescio. However, I think one thing might have got confused in the rewriting:
The original version read:
I think that "Magnesium depletion" is more similar in meaning to "hypomagnesemia" than to "Magnesium deficiency" (or at least that's the implication of the article in the external link). Maybe I'm wrong. But in any case, I think the article should make it clearer what "Magnesium depletion" refers to. -- Arcadian 21:37, 29 October 2005 (UTC)
With regard to the statement that most Americans are not getting enough magnesium, the source doesn't directly state that. I checked the map which came up, clicked on PA, and it said 31 percent of Americans get enough magnesium. If that's true, then almost 70 percent of Americans don't get enough magnesium. Are there more sources to clarify this? Is there at least a better source than the current one? Even though it seems credible, it's very hard to understand exactly what is being stated on that webpage. I'm going to tag this article accordingly. 72.92.16.129 ( talk) 00:36, 27 June 2008 (UTC)
Why is one of the sources a book by Gillian McKeith? Her scientific credentials were discredited some time ago - she purchased her doctorate - and wikipedia shouldn't be referencing such an unreliable source. —Preceding unsigned comment added by 160.39.193.154 ( talk) 21:00, 23 February 2010 (UTC)
"Magnesium sulfate (Epsom salts) has been recommended as a magnesium source, but the sulfate content makes it more laxative than other soluble magnesium sources, so it must sometimes be limited in dose, due to this side effect."
This seems to imply that magnesium sulphate acts as a laxative because of the sulphate. If this were true than Magnesium Hydroxide (a notable laxative) would not be a laxative. If there is a citation that says specifically that in the case of epsom salts the laxative effect is due largely to the sulphate, then it could be put back in. Fireemblem555 ( talk) 06:30, 31 October 2009 (UTC)
Magnesium's beneficial effects in inhibiting neurogenic release of inflammatory cytokines may help explain why magnesium deficiency is recognized to correlate with migraine and MCS by sufferers and treating physicians.
Weglicki WB, Phillips TM.
Pathobiology of magnesium deficiency: a cytokine/neurogenic inflammation hypothesis.
Am J Physiol. 1992 Sep;263(3 Pt 2):R734-7. Department of Medicine, George Washington University Medical Center, Washington, DC 20037.
During the progression of Mg deficiency in a rodent model, we have observed dramatic increases in serum levels of inflammatory cytokines [interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha)] after 3 wk on a Mg-deficient diet. Sequential analyses of these cytokine changes in the serum of rats revealed an initial rise at day 12, followed by a major elevation in all three cytokine levels by day 21. Of greater interest was an early peak in the serum level of the neuropeptide substance P after only 5 days on the diet. This "neuronal" tachykinin is thought to be released from neural tissues, and it is known to stimulate production of certain cytokines, including IL-1, IL-6, and TNF-alpha. In addition, there was a concomitant increase in histamine levels, which may have resulted from stimulation and degranulation of mast cells by substance P. Thus we hypothesize that the release of substance P may be the earliest pathophysiological event leading to stimulation of the inflammatory cytokines, which may then stimulate the free radical mechanisms of injury previously confirmed by our work. —Preceding unsigned comment added by Ocdcntx ( talk • contribs) 19:01, 28 February 2010 (UTC)
The makers of DermaMag claim people absorb magnesium from their proprietary skin lotion far more effectively than they absorb oral magnesium. Does skin absorb any magnesium? If so, how effectively? What forms are how absorbable? Verdant C ( talk) 01:56, 1 December 2010 (UTC)
'Verdant C', when they said: "...people absorb magnesium from their proprietary skin lotion far more effectively than they absorb oral magnesium", they were probably referring to oral magnesium SUPPLEMENTS and not magnesium from food intake. Since the magnesium in food is combined with many other nutrients, you will probably find that absorption is better from food than from supplements. However magnesium chloride oils are absorbed through the skin quite effectively and work well for people with muscular aches and pains. There is some evidence that it can get directly into the bloodstream via the skin much QUICKER than any oral method. This is more often known to occur with nicotine patches on the skin and with morphine patches on the skin for pain relief. If it works with morphine and nicotine, then I am pretty sure it also works with magnesium.-- 197.79.0.1 ( talk) 19:08, 31 May 2013 (UTC)
For the record, magnesium absorption from supplements is actually better than food, provided the supplements are of the soluble type, and not the oxide or hydroxide that rely on stomach acid to solubilize. S B H arris 20:39, 31 May 2013 (UTC)
Information on this compound would be appreciated if anybody has information/links on the latest supplement being pushed. It's claim to fame is the least diarrhea, side effects and best bioavailability from oral supplementation. I understand the 'bis' indicates it is bonded to the magnesium twice but I am not a chemistry person. 99.251.114.120 ( talk) 03:13, 28 March 2012 (UTC)
Magnesium deficiency can't be treated by eating more foods containing magnesium? By the way, what are they? That's what i expected to read in the article. DyNama ( talk) 19:57, 5 August 2012 (UTC)
I'm proposing this merge because I think that these two articles would be better covered together, rather than separately. This is because:
The only difference is that one is low levels in the acute setting and the other is low levels in a chronic setting. It would be better to cover these in the same article under a classification heading. If these are to be merged, I think that this article would be a more accurate title than hypomagnesemia, as it is technically true that a person chronically deficient in magnesium could have, in the acute setting, normal magnesium levels. Would value comments. LT90001 ( talk) 07:55, 29 August 2013 (UTC)
Not sure these are different things. The terms are more or less used interchangeably. Blood levels reflect body levels. Will look at the sources further but looking at merging. Doc James ( talk · contribs · email) 13:13, 10 October 2018 (UTC)
This article seems like an appropriate place to list the detailed RDA advice from various authorities in various countries.
It is a peculiar situation that most US and other modern westerners (at least) ingest much less Magnesium than recommended. Which raises an obvious serious issue of whether most of the population is actually at risk or suffering -- or if the level is set too high. Please add more details about the history of the RDA level-setting processes for dietary Magn, with appropriate sources.
In this case, it would be particularly apt to also include Estimated Average Requirements (EAR) numbers. The Dietary Reference Intake article currently says:
- 71.174.180.38 ( talk) 22:12, 6 September 2016 (UTC)
![]() | This article is rated Start-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | ||||||||||
|
![]() | Ideal sources for Wikipedia's health content are defined in the guideline
Wikipedia:Identifying reliable sources (medicine) and are typically
review articles. Here are links to possibly useful sources of information about Magnesium deficiency.
|
In the chapter titled "Incidence/prevalence" it is stated: "A less than recommended dietary intake does not necessarily imply magnesium deficiency in an individual" There is no citation to back this up and it does not make logical sense either as the RDA was set up specifically to help prevent deficiencies.
I request permission to remove this sentence.-- 197.79.0.1 ( talk) 19:14, 31 May 2013 (UTC)
Nobody here is acknowledging my edit request. I am going ahead with the edit, please do not reverse it without explaining here first.-- 197.79.8.214 ( talk) 18:52, 7 June 2013 (UTC)
On the Magnesium page, under "Biological roles",
[1] it states that "Human magnesium deficiency (including conditions that show few overt symptoms) is relatively rare" with a link to the following NIH page.
[2] There, a fair way down, under "Magnesium Deficiency",
[3] it states "Symptomatic magnesium deficiency due to low dietary intake in otherwise-healthy people is uncommon because the kidneys limit urinary excretion of this mineral" along with a footnote link to a cited source for that information. It sounds like higher intake means your body eliminates the excess, and lower intake means it hangs onto it, so you really need to have some issues before you have symptoms. That's what all the information I've seen on these pages implies. I'm sure someone with more knowledge than I have could find all the sources and put them together.
96.39.170.184 (
talk)
18:04, 1 July 2014 (UTC) C.S. Rowan
References
Very nice job on the rewriting and fleshing out, Nescio. However, I think one thing might have got confused in the rewriting:
The original version read:
I think that "Magnesium depletion" is more similar in meaning to "hypomagnesemia" than to "Magnesium deficiency" (or at least that's the implication of the article in the external link). Maybe I'm wrong. But in any case, I think the article should make it clearer what "Magnesium depletion" refers to. -- Arcadian 21:37, 29 October 2005 (UTC)
With regard to the statement that most Americans are not getting enough magnesium, the source doesn't directly state that. I checked the map which came up, clicked on PA, and it said 31 percent of Americans get enough magnesium. If that's true, then almost 70 percent of Americans don't get enough magnesium. Are there more sources to clarify this? Is there at least a better source than the current one? Even though it seems credible, it's very hard to understand exactly what is being stated on that webpage. I'm going to tag this article accordingly. 72.92.16.129 ( talk) 00:36, 27 June 2008 (UTC)
Why is one of the sources a book by Gillian McKeith? Her scientific credentials were discredited some time ago - she purchased her doctorate - and wikipedia shouldn't be referencing such an unreliable source. —Preceding unsigned comment added by 160.39.193.154 ( talk) 21:00, 23 February 2010 (UTC)
"Magnesium sulfate (Epsom salts) has been recommended as a magnesium source, but the sulfate content makes it more laxative than other soluble magnesium sources, so it must sometimes be limited in dose, due to this side effect."
This seems to imply that magnesium sulphate acts as a laxative because of the sulphate. If this were true than Magnesium Hydroxide (a notable laxative) would not be a laxative. If there is a citation that says specifically that in the case of epsom salts the laxative effect is due largely to the sulphate, then it could be put back in. Fireemblem555 ( talk) 06:30, 31 October 2009 (UTC)
Magnesium's beneficial effects in inhibiting neurogenic release of inflammatory cytokines may help explain why magnesium deficiency is recognized to correlate with migraine and MCS by sufferers and treating physicians.
Weglicki WB, Phillips TM.
Pathobiology of magnesium deficiency: a cytokine/neurogenic inflammation hypothesis.
Am J Physiol. 1992 Sep;263(3 Pt 2):R734-7. Department of Medicine, George Washington University Medical Center, Washington, DC 20037.
During the progression of Mg deficiency in a rodent model, we have observed dramatic increases in serum levels of inflammatory cytokines [interleukin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha)] after 3 wk on a Mg-deficient diet. Sequential analyses of these cytokine changes in the serum of rats revealed an initial rise at day 12, followed by a major elevation in all three cytokine levels by day 21. Of greater interest was an early peak in the serum level of the neuropeptide substance P after only 5 days on the diet. This "neuronal" tachykinin is thought to be released from neural tissues, and it is known to stimulate production of certain cytokines, including IL-1, IL-6, and TNF-alpha. In addition, there was a concomitant increase in histamine levels, which may have resulted from stimulation and degranulation of mast cells by substance P. Thus we hypothesize that the release of substance P may be the earliest pathophysiological event leading to stimulation of the inflammatory cytokines, which may then stimulate the free radical mechanisms of injury previously confirmed by our work. —Preceding unsigned comment added by Ocdcntx ( talk • contribs) 19:01, 28 February 2010 (UTC)
The makers of DermaMag claim people absorb magnesium from their proprietary skin lotion far more effectively than they absorb oral magnesium. Does skin absorb any magnesium? If so, how effectively? What forms are how absorbable? Verdant C ( talk) 01:56, 1 December 2010 (UTC)
'Verdant C', when they said: "...people absorb magnesium from their proprietary skin lotion far more effectively than they absorb oral magnesium", they were probably referring to oral magnesium SUPPLEMENTS and not magnesium from food intake. Since the magnesium in food is combined with many other nutrients, you will probably find that absorption is better from food than from supplements. However magnesium chloride oils are absorbed through the skin quite effectively and work well for people with muscular aches and pains. There is some evidence that it can get directly into the bloodstream via the skin much QUICKER than any oral method. This is more often known to occur with nicotine patches on the skin and with morphine patches on the skin for pain relief. If it works with morphine and nicotine, then I am pretty sure it also works with magnesium.-- 197.79.0.1 ( talk) 19:08, 31 May 2013 (UTC)
For the record, magnesium absorption from supplements is actually better than food, provided the supplements are of the soluble type, and not the oxide or hydroxide that rely on stomach acid to solubilize. S B H arris 20:39, 31 May 2013 (UTC)
Information on this compound would be appreciated if anybody has information/links on the latest supplement being pushed. It's claim to fame is the least diarrhea, side effects and best bioavailability from oral supplementation. I understand the 'bis' indicates it is bonded to the magnesium twice but I am not a chemistry person. 99.251.114.120 ( talk) 03:13, 28 March 2012 (UTC)
Magnesium deficiency can't be treated by eating more foods containing magnesium? By the way, what are they? That's what i expected to read in the article. DyNama ( talk) 19:57, 5 August 2012 (UTC)
I'm proposing this merge because I think that these two articles would be better covered together, rather than separately. This is because:
The only difference is that one is low levels in the acute setting and the other is low levels in a chronic setting. It would be better to cover these in the same article under a classification heading. If these are to be merged, I think that this article would be a more accurate title than hypomagnesemia, as it is technically true that a person chronically deficient in magnesium could have, in the acute setting, normal magnesium levels. Would value comments. LT90001 ( talk) 07:55, 29 August 2013 (UTC)
Not sure these are different things. The terms are more or less used interchangeably. Blood levels reflect body levels. Will look at the sources further but looking at merging. Doc James ( talk · contribs · email) 13:13, 10 October 2018 (UTC)
This article seems like an appropriate place to list the detailed RDA advice from various authorities in various countries.
It is a peculiar situation that most US and other modern westerners (at least) ingest much less Magnesium than recommended. Which raises an obvious serious issue of whether most of the population is actually at risk or suffering -- or if the level is set too high. Please add more details about the history of the RDA level-setting processes for dietary Magn, with appropriate sources.
In this case, it would be particularly apt to also include Estimated Average Requirements (EAR) numbers. The Dietary Reference Intake article currently says:
- 71.174.180.38 ( talk) 22:12, 6 September 2016 (UTC)