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Would this compound be similar to sugar alcohols in which it has a low impact on blood sugar like sucralose like splenda? I notice this is in many different types of food and drink, so I would appreciate any answers on this. -- Cyberman 21:26, August 27, 2005 (UTC)
Is there any proof of this? I can't find any. Link?
I'm pretty sure Trident has switched to Xylitol. But perhaps it's just in their regular stick gum.
Why does this page say that Acesulfame Potassium is 100-200 times sweeter than sugar and half as sweet as aspartame whereas the aspartame page states that aspartame is only 160 times as sweet as sugar?
Why is acesulfame k never mentioned anywhere on food product labels except in the ingredients section? There also seems to be no mention of acesulfame k anywhere in the popular media. Unlike other artificial sweeteners, such as saccarine, marketers seem to have sneaked acesulfame k into all sorts of food products, even into many so-called "health foods," without promoting the sweetener's presence on the promotional sections of the label. Since there are doubts about acesulfame k's claimed safety, one gets the idea that the public is serving as guinea pigs in lieu of exhaustive, pre-marketing safety testing.
Since acesulfame potassium is the potassium salt of acesulfame, shouldn't the structure be shown as a potassium cation and a large organic anion, rather than with a K-N covalent bond, as the article currently does? Compare [1], for example. Chuck 20:11, 7 November 2005 (UTC)
Isn't a concession for the layperson using the encyclopedia? It seems like it. It must appear so in the ingredient list. — Preceding unsigned comment added by 71.187.132.162 ( talk) 09:49, 27 February 2012 (UTC)
What is the potassium amount per serving in sugar free Jello - can this sweetener be used in a low potassium diet as for kidney failure? Herta Dalthorp,Nov 28th 2005.
Hardly an unbiased source of information, I'd think, re the reference at the very end of the article. Is that an advertisement injection?
I don't understand the point of this sentence:
What does this have to do with anything? It reminds me of Splenda's retarded slogan, "It's made from sugar so it tastes like sugar.". Puh-leez. — Keenan Pepper 23:07, 10 July 2006 (UTC)
Well, there could very well be impurities. — Preceding unsigned comment added by 71.187.132.162 ( talk) 09:50, 27 February 2012 (UTC)
Acesufame potassium is suspected as cause of allergic reactions in some people. It is as active ingredient in many enriched waters and mixes for water like Crystal Light, Vita Rain (sold under the Kirkland Brand from Costco) and some Sobe drinks. It can trigger reactions which can include hives ( Urticaria) or other allergic reactions. There have been few clinical trials on humans to date, but lab testing on animals have shown some problems including tumors to the lungs.
[Acesulfame potassium] http://ific.org/publications/brochures/acekbroch.cfm is not metabolized or stored in the body. After it is consumed, it is quickly absorbed by the body and then rapidly excreted unchanged.
-- 64.122.164.5 ( talk) 20:07, 28 April 2008 (UTC)Geoff Williams
The specification of the chemical in the Chinese standard of Q/62170131-X.4 - 2008 —Preceding unsigned comment added by 124.78.208.107 ( talk) 10:25, 30 March 2009 (UTC)
Are there any published scientific reports or relative references attached to those specifications in the following?
http://www.codexalimentarius.net/gsfaonline/additives/details.html?d-3586470-o=2&id=104&d-3586470-s=5&print=true —Preceding unsigned comment added by 124.78.208.107 ( talk) 12:06, 30 March 2009 (UTC)
-- 222.67.205.17 ( talk) 09:56, 4 February 2010 (UTC)
Reference 8 is not in proper form. There is no way to identify this source. I propose to delete the sentence it supports unless the reference can be fixed. 96.35.172.222 ( talk) 21:35, 26 July 2010 (UTC)
I've been searching the information super highway for this for abt 10 mins and havent found it in useable form. That would exclude the cryptic International Phonetic Standard or whatever. 24.0.113.90 ( talk) 11:10, 12 June 2012 (UTC)
Never mind: ay-see-SUHL-faym 24.0.113.90 ( talk) 11:30, 12 June 2012 (UTC)
If they want it to be pronounced ay-see-SUHL-faym then it should be spelled ayseesulfaym or something consistent with the pronunciation. Given the spelling Acesulfame it should be pronounced a-ses-ul-fame. Sam Tomato ( talk) 06:02, 16 January 2019 (UTC)
I have reverted the addition of a reference (see below) which does not discuss acesulfame (although it is mentioned once, it was nowhere a topic of discussion) as synthesis. The existing reference was a letter written in response to the added source, however the article text had existed without the supplemental reference which offers no content specific content which could be classified as a criticism of acesulfame. I have deleted it (part of the WP:BOLD, revert, discuss cycle) and await additional opinions. There has be some discussion on my talk page.
Added reference: Soffritti, M.; Belpoggi, F.; Esposti, D. D.; Lambertini, L.; Tibaldi, E.; Rigano, A. (2006).
"First Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats" (pdf). Environmental Health Perspectives. 114 (3): 379–385.
doi:
10.1289/ehp.8711.
PMC
1392232.{{
cite journal}}
: CS1 maint: multiple names: authors list (
link)
Letter: Karstadt, M. L. (2006). "Testing Needed for Acesulfame Potassium, an Artificial Sweetener" (pdf). Environmental Health Perspectives. 114 (9): A516. doi: 10.1289/ehp.114-a516a. PMC 1570055. PMID 16966071. (also includes already cited letter by the journal article's author)
not signed by: Novangelis
Well, obviously ref Karstadt does not "criticize acesulfame" but "criticizes the NTP methodology" of a shorter test on transgenic mice vs. the full length study by Soffritti. (cited above, in his study of aspartame)
This NTP short test with transgenic mice has found no hints of carcinogenicity (of aspartame!), while the full length results of Soffritti found carcinogenic potential (in aspartame!) So Karstadt finds concerns supported for insufficient sensitivity of the NTP method from this comparison. Consequently submitted a request for further testing of acesulfame with a full length 2 year test. Suffritti responded to this.
The full length study of Suffritti (even if on a different substance, namely aspartame!), which turned out to be the more sensitive method has been cited by Karstadt in comparison to the NTP transgenic mice "short test". The whole discussion sofar is about the NTP test method, not acesulfame, but Karstadt proposes to use the long test as by Soffritti on acesulfame, because it is more sensitive. I have included Soffritti as supplemental ref to see what Karstadt is talking about.(also named as supplemental reading to Karstadt by pubmed central, if you follow the pmc link of ref Karstadt.)
70.137.130.42 (
talk)
06:27, 8 August 2012 (UTC)
I find the anecdote about the accidental discovery of Ace-K suspicious, mainly because it is identical to the purported discovery of Aspartame. Also, these sorts of stories of scientific serendipity are usually apocryphal. In other words, too finger-licking-good to be true.
From Acesulfame potassium page: "After accidentally dipping his fingers into the chemicals that he was working with, Clauss licked them to pick up a piece of paper." From Aspartame page: "[Schlatter] accidentally discovered its sweet taste when he licked his finger, which had become contaminated with aspartame, to lift up a piece of paper."
— Preceding unsigned comment added by 24.22.241.190 ( talk) 02:47, 17 August 2012 (UTC)
Personally, I'd like to know what they were researching. The structure is similar to a highly-modified barbituate in not-entirely-superficial ways; was it anesthetics research? -- John Moser ( talk) 16:46, 30 May 2017 (UTC)
The text reads: "However, a similar study conducted with p53 haploinsufficient mice showed signs of carcinogenicity in males but not females.[13]"
Here is Reference 13: [13] National Toxicology Program (2005). "Toxicity Studies of Acesulfame Potassium (CAS No. 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies)" (PDF). Genetically Modified Model Report (National Institutes of Health) 2005 (NTP GMM-2): 1–113. PMID 18784762. NIH Publication No. 06-4460.
The study concludes that: “Under the conditions of this 9-month feed study, there was no evidence of carcinogenic activity of acesulfame potassium in male or female p53 haploinsufficient mice exposed to 0.3%, 1%, or 3%.”, i.e., it does not state that it “showed signs of carcinogenicity in males”. I suggest the corresponding sentence should be removed. — Preceding unsigned comment added by Carlos-alberto-teixeira ( talk • contribs) 15:57, 2 December 2014 (UTC)
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To note, I removed the link from the text "acetoacetamide" that linked to wikipedia:Acetamide; these are two separate chemical compounds. Unfortunately there is not yet a page for the compound referenced here (acetoacetamide.) morsontologica ( talk) 02:51, 9 May 2020 (UTC)
This is the
talk page for discussing improvements to the
Acesulfame potassium article. This is not a forum for general discussion of the article's subject. |
Article policies
|
Find sources: Google ( books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL |
![]() | This article is rated C-class on Wikipedia's
content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||||||||||||||||
|
Would this compound be similar to sugar alcohols in which it has a low impact on blood sugar like sucralose like splenda? I notice this is in many different types of food and drink, so I would appreciate any answers on this. -- Cyberman 21:26, August 27, 2005 (UTC)
Is there any proof of this? I can't find any. Link?
I'm pretty sure Trident has switched to Xylitol. But perhaps it's just in their regular stick gum.
Why does this page say that Acesulfame Potassium is 100-200 times sweeter than sugar and half as sweet as aspartame whereas the aspartame page states that aspartame is only 160 times as sweet as sugar?
Why is acesulfame k never mentioned anywhere on food product labels except in the ingredients section? There also seems to be no mention of acesulfame k anywhere in the popular media. Unlike other artificial sweeteners, such as saccarine, marketers seem to have sneaked acesulfame k into all sorts of food products, even into many so-called "health foods," without promoting the sweetener's presence on the promotional sections of the label. Since there are doubts about acesulfame k's claimed safety, one gets the idea that the public is serving as guinea pigs in lieu of exhaustive, pre-marketing safety testing.
Since acesulfame potassium is the potassium salt of acesulfame, shouldn't the structure be shown as a potassium cation and a large organic anion, rather than with a K-N covalent bond, as the article currently does? Compare [1], for example. Chuck 20:11, 7 November 2005 (UTC)
Isn't a concession for the layperson using the encyclopedia? It seems like it. It must appear so in the ingredient list. — Preceding unsigned comment added by 71.187.132.162 ( talk) 09:49, 27 February 2012 (UTC)
What is the potassium amount per serving in sugar free Jello - can this sweetener be used in a low potassium diet as for kidney failure? Herta Dalthorp,Nov 28th 2005.
Hardly an unbiased source of information, I'd think, re the reference at the very end of the article. Is that an advertisement injection?
I don't understand the point of this sentence:
What does this have to do with anything? It reminds me of Splenda's retarded slogan, "It's made from sugar so it tastes like sugar.". Puh-leez. — Keenan Pepper 23:07, 10 July 2006 (UTC)
Well, there could very well be impurities. — Preceding unsigned comment added by 71.187.132.162 ( talk) 09:50, 27 February 2012 (UTC)
Acesufame potassium is suspected as cause of allergic reactions in some people. It is as active ingredient in many enriched waters and mixes for water like Crystal Light, Vita Rain (sold under the Kirkland Brand from Costco) and some Sobe drinks. It can trigger reactions which can include hives ( Urticaria) or other allergic reactions. There have been few clinical trials on humans to date, but lab testing on animals have shown some problems including tumors to the lungs.
[Acesulfame potassium] http://ific.org/publications/brochures/acekbroch.cfm is not metabolized or stored in the body. After it is consumed, it is quickly absorbed by the body and then rapidly excreted unchanged.
-- 64.122.164.5 ( talk) 20:07, 28 April 2008 (UTC)Geoff Williams
The specification of the chemical in the Chinese standard of Q/62170131-X.4 - 2008 —Preceding unsigned comment added by 124.78.208.107 ( talk) 10:25, 30 March 2009 (UTC)
Are there any published scientific reports or relative references attached to those specifications in the following?
http://www.codexalimentarius.net/gsfaonline/additives/details.html?d-3586470-o=2&id=104&d-3586470-s=5&print=true —Preceding unsigned comment added by 124.78.208.107 ( talk) 12:06, 30 March 2009 (UTC)
-- 222.67.205.17 ( talk) 09:56, 4 February 2010 (UTC)
Reference 8 is not in proper form. There is no way to identify this source. I propose to delete the sentence it supports unless the reference can be fixed. 96.35.172.222 ( talk) 21:35, 26 July 2010 (UTC)
I've been searching the information super highway for this for abt 10 mins and havent found it in useable form. That would exclude the cryptic International Phonetic Standard or whatever. 24.0.113.90 ( talk) 11:10, 12 June 2012 (UTC)
Never mind: ay-see-SUHL-faym 24.0.113.90 ( talk) 11:30, 12 June 2012 (UTC)
If they want it to be pronounced ay-see-SUHL-faym then it should be spelled ayseesulfaym or something consistent with the pronunciation. Given the spelling Acesulfame it should be pronounced a-ses-ul-fame. Sam Tomato ( talk) 06:02, 16 January 2019 (UTC)
I have reverted the addition of a reference (see below) which does not discuss acesulfame (although it is mentioned once, it was nowhere a topic of discussion) as synthesis. The existing reference was a letter written in response to the added source, however the article text had existed without the supplemental reference which offers no content specific content which could be classified as a criticism of acesulfame. I have deleted it (part of the WP:BOLD, revert, discuss cycle) and await additional opinions. There has be some discussion on my talk page.
Added reference: Soffritti, M.; Belpoggi, F.; Esposti, D. D.; Lambertini, L.; Tibaldi, E.; Rigano, A. (2006).
"First Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats" (pdf). Environmental Health Perspectives. 114 (3): 379–385.
doi:
10.1289/ehp.8711.
PMC
1392232.{{
cite journal}}
: CS1 maint: multiple names: authors list (
link)
Letter: Karstadt, M. L. (2006). "Testing Needed for Acesulfame Potassium, an Artificial Sweetener" (pdf). Environmental Health Perspectives. 114 (9): A516. doi: 10.1289/ehp.114-a516a. PMC 1570055. PMID 16966071. (also includes already cited letter by the journal article's author)
not signed by: Novangelis
Well, obviously ref Karstadt does not "criticize acesulfame" but "criticizes the NTP methodology" of a shorter test on transgenic mice vs. the full length study by Soffritti. (cited above, in his study of aspartame)
This NTP short test with transgenic mice has found no hints of carcinogenicity (of aspartame!), while the full length results of Soffritti found carcinogenic potential (in aspartame!) So Karstadt finds concerns supported for insufficient sensitivity of the NTP method from this comparison. Consequently submitted a request for further testing of acesulfame with a full length 2 year test. Suffritti responded to this.
The full length study of Suffritti (even if on a different substance, namely aspartame!), which turned out to be the more sensitive method has been cited by Karstadt in comparison to the NTP transgenic mice "short test". The whole discussion sofar is about the NTP test method, not acesulfame, but Karstadt proposes to use the long test as by Soffritti on acesulfame, because it is more sensitive. I have included Soffritti as supplemental ref to see what Karstadt is talking about.(also named as supplemental reading to Karstadt by pubmed central, if you follow the pmc link of ref Karstadt.)
70.137.130.42 (
talk)
06:27, 8 August 2012 (UTC)
I find the anecdote about the accidental discovery of Ace-K suspicious, mainly because it is identical to the purported discovery of Aspartame. Also, these sorts of stories of scientific serendipity are usually apocryphal. In other words, too finger-licking-good to be true.
From Acesulfame potassium page: "After accidentally dipping his fingers into the chemicals that he was working with, Clauss licked them to pick up a piece of paper." From Aspartame page: "[Schlatter] accidentally discovered its sweet taste when he licked his finger, which had become contaminated with aspartame, to lift up a piece of paper."
— Preceding unsigned comment added by 24.22.241.190 ( talk) 02:47, 17 August 2012 (UTC)
Personally, I'd like to know what they were researching. The structure is similar to a highly-modified barbituate in not-entirely-superficial ways; was it anesthetics research? -- John Moser ( talk) 16:46, 30 May 2017 (UTC)
The text reads: "However, a similar study conducted with p53 haploinsufficient mice showed signs of carcinogenicity in males but not females.[13]"
Here is Reference 13: [13] National Toxicology Program (2005). "Toxicity Studies of Acesulfame Potassium (CAS No. 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies)" (PDF). Genetically Modified Model Report (National Institutes of Health) 2005 (NTP GMM-2): 1–113. PMID 18784762. NIH Publication No. 06-4460.
The study concludes that: “Under the conditions of this 9-month feed study, there was no evidence of carcinogenic activity of acesulfame potassium in male or female p53 haploinsufficient mice exposed to 0.3%, 1%, or 3%.”, i.e., it does not state that it “showed signs of carcinogenicity in males”. I suggest the corresponding sentence should be removed. — Preceding unsigned comment added by Carlos-alberto-teixeira ( talk • contribs) 15:57, 2 December 2014 (UTC)
Hello fellow Wikipedians,
I have just modified 3 external links on Acesulfame potassium. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
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Cheers.— InternetArchiveBot ( Report bug) 09:25, 3 October 2016 (UTC)
Hello fellow Wikipedians,
I have just modified 3 external links on Acesulfame potassium. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:
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Cheers.— InternetArchiveBot ( Report bug) 23:46, 25 June 2017 (UTC)
To note, I removed the link from the text "acetoacetamide" that linked to wikipedia:Acetamide; these are two separate chemical compounds. Unfortunately there is not yet a page for the compound referenced here (acetoacetamide.) morsontologica ( talk) 02:51, 9 May 2020 (UTC)