From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
RCAN2 is a
gene that in humans encodes for the
protein
Calcipressin -2.
Calcipressin-2 is a protein that in humans is encoded by the RCAN2 gene.
[5]
[6]
Summary box
N/A
See also
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000172348 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000039601 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Miyazaki T, Kanou Y, Murata Y, Ohmori S, Niwa T, Maeda K, Yamamura H, Seo H (Aug 1996).
"Molecular cloning of a novel thyroid hormone-responsive gene, ZAKI-4, in human skin fibroblasts" . J Biol Chem . 271 (24): 14567–71.
doi :
10.1074/jbc.271.24.14567 .
PMID
8662924 .
^
"Entrez Gene: DSCR1L1 Down syndrome critical region gene 1-like 1" .
Further reading
Bonaldo MF, Lennon G, Soares MB (1997).
"Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Res . 6 (9): 791–806.
doi :
10.1101/gr.6.9.791 .
PMID
8889548 .
Rothermel B, Vega RB, Yang J, et al. (2000).
"A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling" . J. Biol. Chem . 275 (12): 8719–25.
doi :
10.1074/jbc.275.12.8719 .
PMID
10722714 .
Strippoli P, Lenzi L, Petrini M, et al. (2000). "A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)". Genomics . 64 (3): 252–63.
doi :
10.1006/geno.2000.6127 .
PMID
10756093 .
Fuentes JJ, Genescà L, Kingsbury TJ, et al. (2000).
"DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways" . Hum. Mol. Genet . 9 (11): 1681–90.
doi :
10.1093/hmg/9.11.1681 .
PMID
10861295 .
Cao X, Kambe F, Miyazaki T, et al. (2002).
"Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors" . Biochem. J . 367 (Pt 2): 459–66.
doi :
10.1042/BJ20011797 .
PMC
1222895 .
PMID
12102656 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
"Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65.
doi :
10.1101/gr.4039406 .
PMC
1356129 .
PMID
16344560 .
Qin L, Zhao D, Liu X, et al. (2007).
"Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway" . Mol. Cancer Res . 4 (11): 811–20.
doi :
10.1158/1541-7786.MCR-06-0126 .
PMID
17114339 .
Gollogly LK, Ryeom SW, Yoon SS (2007).
"Down syndrome candidate region 1-like 1 (DSCR1-L1) mimics the inhibitory effects of DSCR1 on calcineurin signaling in endothelial cells and inhibits angiogenesis" . J. Surg. Res . 142 (1): 129–36.
doi :
10.1016/j.jss.2006.10.011 .
PMC
1995402 .
PMID
17610901 .
External links