Clinical data | |
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Trade names | Medrosol, Promedrol |
Other names | PNU-67590A; U-67590A; Methylprednisolone 21-(8-(methyl-(2-sulfoethyl)amino)-1,8-dioxooctanoate); 11β,17α-Dihydroxy-6α-methyl-21-((8-(methyl(2-sulfoethyl)amino)-1,8-dioxooctyl)oxy)pregna-1,4-diene-3,20-dione |
Routes of administration | Intravenous administration |
Drug class | Corticosteroid; Glucocorticoid |
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CAS Number | |
PubChem CID | |
ChemSpider | |
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ChEBI | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C33H49NO10S |
Molar mass | 651.81 g·mol−1 |
3D model ( JSmol) | |
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Methylprednisolone suleptanate, sold under the brand names Medrosol and Promedrol, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically, the C21 suleptanate 21-(8-(methyl-(2-sulfoethyl)amino)-1,8-dioxooctanoate) ester of methylprednisolone. [1] [2] It acts as a prodrug of methylprednisolone. [3] Methylprednisolone suleptanate was developed as an improved alternative to methylprednisolone acetate (Depo-Medrol) with greater water solubility for use by intravenous administration. [3]
Clinical data | |
---|---|
Trade names | Medrosol, Promedrol |
Other names | PNU-67590A; U-67590A; Methylprednisolone 21-(8-(methyl-(2-sulfoethyl)amino)-1,8-dioxooctanoate); 11β,17α-Dihydroxy-6α-methyl-21-((8-(methyl(2-sulfoethyl)amino)-1,8-dioxooctyl)oxy)pregna-1,4-diene-3,20-dione |
Routes of administration | Intravenous administration |
Drug class | Corticosteroid; Glucocorticoid |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEBI | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C33H49NO10S |
Molar mass | 651.81 g·mol−1 |
3D model ( JSmol) | |
| |
|
Methylprednisolone suleptanate, sold under the brand names Medrosol and Promedrol, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically, the C21 suleptanate 21-(8-(methyl-(2-sulfoethyl)amino)-1,8-dioxooctanoate) ester of methylprednisolone. [1] [2] It acts as a prodrug of methylprednisolone. [3] Methylprednisolone suleptanate was developed as an improved alternative to methylprednisolone acetate (Depo-Medrol) with greater water solubility for use by intravenous administration. [3]