Proglucagon is a
protein that is cleaved from preproglucagon. Preproglucagon in humans is encoded by the GCGgene.[5][6]
Proglucagon is a precursor of
glucagon, and several other components. It is generated in the
alpha cells of the
pancreas and in the intestinal
L cells in the distal ileum and colon. It is also cleaved into the following components in different organs:
Signal peptide (1-20) – removed from preproglucagon to form proglucagon
Proglucagon is a
protein that is cleaved from preproglucagon. Preproglucagon in humans is encoded by the GCGgene.[5][6]
Proglucagon is a precursor of
glucagon, and several other components. It is generated in the
alpha cells of the
pancreas and in the intestinal
L cells in the distal ileum and colon. It is also cleaved into the following components in different organs:
Signal peptide (1-20) – removed from preproglucagon to form proglucagon