LINALOOL DEHYDRATASE

Linalool dehydratase ( EC 4.2.1.127, linalool hydro-lyase (myrcene-forming)) is an enzyme with systematic name (3S)-linalool hydro-lyase (myrcene-forming).^[1]^[2] This enzyme catalyses the following chemical reaction

\rightleftharpoons

myrcene + H₂O

In absence of oxygen this enzyme can also catalyse the isomerization of (3S)-linalool to geraniol.

References

^ Brodkorb D, Gottschall M, Marmulla R, Lüddeke F, Harder J (October 2010). "Linalool dehydratase-isomerase, a bifunctional enzyme in the anaerobic degradation of monoterpenes". The Journal of Biological Chemistry. 285 (40): 30436–42. doi: 10.1074/jbc.m109.084244. PMC 2945536. PMID 20663876.
^ Lüddeke F, Harder J (2011). "Enantiospecific (S)-(+)-linalool formation from beta-myrcene by linalool dehydratase-isomerase". Zeitschrift für Naturforschung C. 66 (7–8): 409–12. doi: 10.5560/znc.2011.66c0409. PMID 21950166.

Linalool+dehydratase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Carbon–oxygen lyases ( EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/ 3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase Pectin lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases ( list) EC2 Transferases ( list) EC3 Hydrolases ( list) EC4 Lyases ( list) EC5 Isomerases ( list) EC6 Ligases ( list) EC7 Translocases ( list)

v t e Carbon–oxygen lyases ( EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/ 3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase Pectin lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases ( list) EC2 Transferases ( list) EC3 Hydrolases ( list) EC4 Lyases ( list) EC5 Isomerases ( list) EC6 Ligases ( list) EC7 Translocases ( list)