| Hepsin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.106 | ||||||||
| CAS no. | 112398-23-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Hepsin ( EC 3.4.21.106) is an enzyme. [1] [2] [3] This enzyme catalyses the following chemical reaction
- Cleavage after basic amino-acid residues, with Arg strongly preferred to Lys
This type-II membrane-associated serine peptidase plays a role in cell growth and development.
- ^ Zhukov A, Hellman U, Ingelman-Sundberg M (January 1997). "Purification and characterization of hepsin from rat liver microsomes". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1337 (1): 85–95. doi: 10.1016/s0167-4838(96)00152-5. PMID 9003440.
- ^ Kazama Y, Hamamoto T, Foster DC, Kisiel W (January 1995). "Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation". The Journal of Biological Chemistry. 270 (1): 66–72. doi: 10.1074/jbc.270.1.66. PMID 7814421.
- ^ Torres-Rosado A, O'Shea KS, Tsuji A, Chou SH, Kurachi K (August 1993). "Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth". Proceedings of the National Academy of Sciences of the United States of America. 90 (15): 7181–5. Bibcode: 1993PNAS...90.7181T. doi: 10.1073/pnas.90.15.7181. PMC 47100. PMID 8346233.
- Hepsin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
 | This enzyme-related article is a stub. You can help Wikipedia by expanding it. |
| Hepsin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.106 | ||||||||
| CAS no. | 112398-23-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Hepsin ( EC 3.4.21.106) is an enzyme. [1] [2] [3] This enzyme catalyses the following chemical reaction
- Cleavage after basic amino-acid residues, with Arg strongly preferred to Lys
This type-II membrane-associated serine peptidase plays a role in cell growth and development.
- ^ Zhukov A, Hellman U, Ingelman-Sundberg M (January 1997). "Purification and characterization of hepsin from rat liver microsomes". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1337 (1): 85–95. doi: 10.1016/s0167-4838(96)00152-5. PMID 9003440.
- ^ Kazama Y, Hamamoto T, Foster DC, Kisiel W (January 1995). "Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation". The Journal of Biological Chemistry. 270 (1): 66–72. doi: 10.1074/jbc.270.1.66. PMID 7814421.
- ^ Torres-Rosado A, O'Shea KS, Tsuji A, Chou SH, Kurachi K (August 1993). "Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth". Proceedings of the National Academy of Sciences of the United States of America. 90 (15): 7181–5. Bibcode: 1993PNAS...90.7181T. doi: 10.1073/pnas.90.15.7181. PMC 47100. PMID 8346233.
- Hepsin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
|
| This enzyme-related article is a stub. You can help Wikipedia by expanding it. |