Clinical data | |
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Trade names | Dynocard |
Other names | Gitoxin 3′,3′,3′′′,4′′′′,16-pentaformate |
ATC code | |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.030.397 |
Chemical and physical data | |
Formula | C46H64O19 |
Molar mass | 920.999 g·mol−1 |
3D model ( JSmol) | |
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(what is this?) (verify) |
Gitoformate ( INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). [1] Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.
Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar. [2] [3] Gitoxin, a cardiac glycoside from the woolly foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside. [4]
Clinical data | |
---|---|
Trade names | Dynocard |
Other names | Gitoxin 3′,3′,3′′′,4′′′′,16-pentaformate |
ATC code | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.030.397 |
Chemical and physical data | |
Formula | C46H64O19 |
Molar mass | 920.999 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(what is this?) (verify) |
Gitoformate ( INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). [1] Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.
Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar. [2] [3] Gitoxin, a cardiac glycoside from the woolly foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside. [4]