From Wikipedia, the free encyclopedia
Deslanoside
Clinical data
AHFS/ Drugs.com International Drug Names
ATC code
Identifiers
  • (3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard ( EPA)
ECHA InfoCard 100.037.774 Edit this at Wikidata
Chemical and physical data
FormulaC47H74O19
Molar mass943.090 g·mol−1
  • InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1 checkY
  • Key:OBATZBGFDSVCJD-LALPQLPRSA-N checkY
   (verify)

Deslanoside (trade name Cedilanide in Brazil [1]) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata, the Woolly Foxglove. [2] [3]

References

  1. ^ "Cedilanide". Drugs.com. Archived from the original on 2019-08-15. Retrieved 2018-01-23.
  2. ^ Bakke OM, Aslaksen A, Lehmann V, Lien E (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of Cardiovascular Pharmacology. 3 (5): 1015–25. doi: 10.1097/00005344-198109000-00012. PMID  6168847.
  3. ^ Budavari S, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN  0911910123, 2967
From Wikipedia, the free encyclopedia
Deslanoside
Clinical data
AHFS/ Drugs.com International Drug Names
ATC code
Identifiers
  • (3β,5β,12β)-3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard ( EPA)
ECHA InfoCard 100.037.774 Edit this at Wikidata
Chemical and physical data
FormulaC47H74O19
Molar mass943.090 g·mol−1
  • InChI=1S/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1 checkY
  • Key:OBATZBGFDSVCJD-LALPQLPRSA-N checkY
   (verify)

Deslanoside (trade name Cedilanide in Brazil [1]) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). It is found in the leaves of Digitalis lanata, the Woolly Foxglove. [2] [3]

References

  1. ^ "Cedilanide". Drugs.com. Archived from the original on 2019-08-15. Retrieved 2018-01-23.
  2. ^ Bakke OM, Aslaksen A, Lehmann V, Lien E (1981). "Pharmacokinetics and serum concentration--effect relationship of intravenous deslanoside". Journal of Cardiovascular Pharmacology. 3 (5): 1015–25. doi: 10.1097/00005344-198109000-00012. PMID  6168847.
  3. ^ Budavari S, ed. (1996), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th ed.), Merck, ISBN  0911910123, 2967

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