FK506-binding protein 8 is a
protein that in humans is encoded by the FKBP8gene.[5][6]
The protein encoded by this gene is a member of the
immunophilin protein family, which play a role in
immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have
PPIase/rotamase activity. It may have a role in
neurons associated with memory function.[6]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Lam E, Martin M, Wiederrecht G (Sep 1995). "Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs". Gene. 160 (2): 297–302.
doi:
10.1016/0378-1119(95)00216-S.
PMID7543869.
Bulgakov OV, Eggenschwiler JT, Hong DH, et al. (2004). "FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues". Development. 131 (9): 2149–59.
doi:
10.1242/dev.01122.
PMID15105374.
S2CID8203913.
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101.
doi:
10.1038/nbt1046.
PMID15592455.
S2CID7200157.
Kang CB, Feng L, Chia J, Yoon HS (2005). "Molecular characterization of FK-506 binding protein 38 and its potential regulatory role on the anti-apoptotic protein Bcl-2". Biochem. Biophys. Res. Commun. 337 (1): 30–8.
doi:
10.1016/j.bbrc.2005.09.023.
hdl:10356/94816.
PMID16176796.
FK506-binding protein 8 is a
protein that in humans is encoded by the FKBP8gene.[5][6]
The protein encoded by this gene is a member of the
immunophilin protein family, which play a role in
immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have
PPIase/rotamase activity. It may have a role in
neurons associated with memory function.[6]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Lam E, Martin M, Wiederrecht G (Sep 1995). "Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs". Gene. 160 (2): 297–302.
doi:
10.1016/0378-1119(95)00216-S.
PMID7543869.
Bulgakov OV, Eggenschwiler JT, Hong DH, et al. (2004). "FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues". Development. 131 (9): 2149–59.
doi:
10.1242/dev.01122.
PMID15105374.
S2CID8203913.
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101.
doi:
10.1038/nbt1046.
PMID15592455.
S2CID7200157.
Kang CB, Feng L, Chia J, Yoon HS (2005). "Molecular characterization of FK-506 binding protein 38 and its potential regulatory role on the anti-apoptotic protein Bcl-2". Biochem. Biophys. Res. Commun. 337 (1): 30–8.
doi:
10.1016/j.bbrc.2005.09.023.
hdl:10356/94816.
PMID16176796.