(Redirected from
FGD2 (gene))
FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene. [5]
It is a member of the FYVE, RhoGEF and PH domain containing family.
- ^ a b c GRCh38: Ensembl release 89: ENSG00000146192 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024013 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: FYVE".
- Salehi AH, Xanthoudakis S, Barker PA (2002). "NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway". J. Biol. Chem. 277 (50): 48043–50. doi: 10.1074/jbc.M205324200. PMID 12376548.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode: 2003Natur.425..805M. doi: 10.1038/nature02055. PMID 14574404.
- Hattori A, Okumura K, Nagase T, et al. (2000). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi: 10.1093/dnares/7.6.357. PMID 11214971.
- Pasteris NG, Gorski JL (1999). "Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues". Genomics. 60 (1): 57–66. doi: 10.1006/geno.1999.5903. PMID 10458911.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi: 10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285. PMID 14702039.
- Harrington AW, Kim JY, Yoon SO (2002). "Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis". J. Neurosci. 22 (1): 156–66. doi: 10.1523/JNEUROSCI.22-01-00156.2002. PMC 6757583. PMID 11756498.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Rabizadeh S, Bredesen DE (2003). "Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR)". Cytokine Growth Factor Rev. 14 (3–4): 225–39. doi: 10.1016/S1359-6101(03)00018-2. PMID 12787561.
- Huber C, Mårtensson A, Bokoch GM, et al. (2008). "FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles". J. Biol. Chem. 283 (49): 34002–12. doi: 10.1074/jbc.M803957200. PMC 2590680. PMID 18838382.
- Delague V, Jacquier A, Hamadouche T, et al. (2007). "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H". Am. J. Hum. Genet. 81 (1): 1–16. doi: 10.1086/518428. PMC 1950914. PMID 17564959.
 | This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it. |
(Redirected from
FGD2 (gene))
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| Aliases | FGD2, ZFYVE4, FYVE, RhoGEF and PH domain containing 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 605091; MGI: 1347084; HomoloGene: 8438; GeneCards: FGD2; OMA: FGD2 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene. [5]
It is a member of the FYVE, RhoGEF and PH domain containing family.
- ^ a b c GRCh38: Ensembl release 89: ENSG00000146192 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024013 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: FYVE".
- Salehi AH, Xanthoudakis S, Barker PA (2002). "NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway". J. Biol. Chem. 277 (50): 48043–50. doi: 10.1074/jbc.M205324200. PMID 12376548.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode: 2003Natur.425..805M. doi: 10.1038/nature02055. PMID 14574404.
- Hattori A, Okumura K, Nagase T, et al. (2000). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi: 10.1093/dnares/7.6.357. PMID 11214971.
- Pasteris NG, Gorski JL (1999). "Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues". Genomics. 60 (1): 57–66. doi: 10.1006/geno.1999.5903. PMID 10458911.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi: 10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285. PMID 14702039.
- Harrington AW, Kim JY, Yoon SO (2002). "Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis". J. Neurosci. 22 (1): 156–66. doi: 10.1523/JNEUROSCI.22-01-00156.2002. PMC 6757583. PMID 11756498.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Rabizadeh S, Bredesen DE (2003). "Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR)". Cytokine Growth Factor Rev. 14 (3–4): 225–39. doi: 10.1016/S1359-6101(03)00018-2. PMID 12787561.
- Huber C, Mårtensson A, Bokoch GM, et al. (2008). "FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles". J. Biol. Chem. 283 (49): 34002–12. doi: 10.1074/jbc.M803957200. PMC 2590680. PMID 18838382.
- Delague V, Jacquier A, Hamadouche T, et al. (2007). "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H". Am. J. Hum. Genet. 81 (1): 1–16. doi: 10.1086/518428. PMC 1950914. PMID 17564959.
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| This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it. |