FYVE, RhoGEF and PH domain-containing protein 4 is a protein encoded in humans by the FGD4 gene. [5] [6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000139132 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022788 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Ikeda W, Nakanishi H, Takekuni K, Itoh S, Takai Y (Aug 2001). "Identification of splicing variants of Frabin with partly different functions and tissue distribution". Biochem Biophys Res Commun. 286 (5): 1066–72. doi: 10.1006/bbrc.2001.5481. PMID 11527409.
- ^ "Entrez Gene: FGD4 FYVE, RhoGEF and PH domain containing 4".
Further reading
- Obaishi H, Nakanishi H, Mandai K, et al. (1998). "Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase". J. Biol. Chem. 273 (30): 18697–700. doi: 10.1074/jbc.273.30.18697. PMID 9668039.
- Ikeda W, Nakanishi H, Tanaka Y, et al. (2001). "Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation". Oncogene. 20 (27): 3457–63. doi: 10.1038/sj.onc.1204463. PMID 11429692. S2CID 27464942.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285. PMID 14702039.
- Chen XM, Splinter PL, Tietz PS, et al. (2004). "Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42". J. Biol. Chem. 279 (30): 31671–8. doi: 10.1074/jbc.M401592200. PMID 15133042.
- De Sandre-Giovannoli A, Delague V, Hamadouche T, et al. (2006). "Homozygosity mapping of autosomal recessive demyelinating Charcot-Marie-Tooth neuropathy (CMT4H) to a novel locus on chromosome 12p11.21-q13.11". J. Med. Genet. 42 (3): 260–5. doi: 10.1136/jmg.2004.024364. PMC 1736004. PMID 15744041.
- Delague V, Jacquier A, Hamadouche T, et al. (2007). "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H". Am. J. Hum. Genet. 81 (1): 1–16. doi: 10.1086/518428. PMC 1950914. PMID 17564959.
- Stendel C, Roos A, Deconinck T, et al. (2007). "Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4". Am. J. Hum. Genet. 81 (1): 158–64. doi: 10.1086/518770. PMC 1950925. PMID 17564972.
External links
 | This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it. |
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| Aliases | FGD4, CMT4H, FRABP, ZFYVE6, FYVE, RhoGEF and PH domain containing 4 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 611104; MGI: 2183747; HomoloGene: 26727; GeneCards: FGD4; OMA: FGD4 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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FYVE, RhoGEF and PH domain-containing protein 4 is a protein encoded in humans by the FGD4 gene. [5] [6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000139132 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022788 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Ikeda W, Nakanishi H, Takekuni K, Itoh S, Takai Y (Aug 2001). "Identification of splicing variants of Frabin with partly different functions and tissue distribution". Biochem Biophys Res Commun. 286 (5): 1066–72. doi: 10.1006/bbrc.2001.5481. PMID 11527409.
- ^ "Entrez Gene: FGD4 FYVE, RhoGEF and PH domain containing 4".
Further reading
- Obaishi H, Nakanishi H, Mandai K, et al. (1998). "Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase". J. Biol. Chem. 273 (30): 18697–700. doi: 10.1074/jbc.273.30.18697. PMID 9668039.
- Ikeda W, Nakanishi H, Tanaka Y, et al. (2001). "Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation". Oncogene. 20 (27): 3457–63. doi: 10.1038/sj.onc.1204463. PMID 11429692. S2CID 27464942.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode: 2002PNAS...9916899M. doi: 10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285. PMID 14702039.
- Chen XM, Splinter PL, Tietz PS, et al. (2004). "Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42". J. Biol. Chem. 279 (30): 31671–8. doi: 10.1074/jbc.M401592200. PMID 15133042.
- De Sandre-Giovannoli A, Delague V, Hamadouche T, et al. (2006). "Homozygosity mapping of autosomal recessive demyelinating Charcot-Marie-Tooth neuropathy (CMT4H) to a novel locus on chromosome 12p11.21-q13.11". J. Med. Genet. 42 (3): 260–5. doi: 10.1136/jmg.2004.024364. PMC 1736004. PMID 15744041.
- Delague V, Jacquier A, Hamadouche T, et al. (2007). "Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H". Am. J. Hum. Genet. 81 (1): 1–16. doi: 10.1086/518428. PMC 1950914. PMID 17564959.
- Stendel C, Roos A, Deconinck T, et al. (2007). "Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4". Am. J. Hum. Genet. 81 (1): 158–64. doi: 10.1086/518770. PMC 1950925. PMID 17564972.
External links
|
| This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it. |