From Wikipedia, the free encyclopedia
engulfment and cell motility 3
Identifiers
SymbolELMO3
Alt. symbolsCED12, FLJ13824
NCBI gene 79767
HGNC 17289
OMIM 606422
RefSeq NM_024712
UniProt Q96BJ8
Other data
Locus Chr. 16 q22.1
Search for
Structures Swiss-model
Domains InterPro

Engulfment and cell motility 3, also known as ELMO3, is a human gene. [1] [2]

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility ( ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 ( DOCK1) protein to promote phagocytosis and effect cell shape changes. [1]

References

  1. ^ a b "Entrez Gene: ELMO3 engulfment and cell motility 3". Archived from the original on 2010-12-05. Retrieved 2017-08-31.
  2. ^ Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS (October 2001). "CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration" (PDF). Cell. 107 (1): 27–41. doi: 10.1016/S0092-8674(01)00520-7. PMID  11595183. S2CID  15232864. Archived from the original (PDF) on 2018-07-19. Retrieved 2019-09-18.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


From Wikipedia, the free encyclopedia
engulfment and cell motility 3
Identifiers
SymbolELMO3
Alt. symbolsCED12, FLJ13824
NCBI gene 79767
HGNC 17289
OMIM 606422
RefSeq NM_024712
UniProt Q96BJ8
Other data
Locus Chr. 16 q22.1
Search for
Structures Swiss-model
Domains InterPro

Engulfment and cell motility 3, also known as ELMO3, is a human gene. [1] [2]

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility ( ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 ( DOCK1) protein to promote phagocytosis and effect cell shape changes. [1]

References

  1. ^ a b "Entrez Gene: ELMO3 engulfment and cell motility 3". Archived from the original on 2010-12-05. Retrieved 2017-08-31.
  2. ^ Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS (October 2001). "CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration" (PDF). Cell. 107 (1): 27–41. doi: 10.1016/S0092-8674(01)00520-7. PMID  11595183. S2CID  15232864. Archived from the original (PDF) on 2018-07-19. Retrieved 2019-09-18.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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