 | |
| Clinical data | |
|---|---|
| AHFS/ Drugs.com | International Drug Names |
|
Pregnancy category |
|
|
Routes of administration | Oral |
| ATC code | |
| Pharmacokinetic data | |
| Protein binding | 88% |
| Elimination half-life | 5 to 10 hours |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard ( EPA) | |
| ECHA InfoCard | 100.001.323 |
| Chemical and physical data | |
| Formula | C15H10O2 |
| Molar mass | 222.243 g·mol−1 |
| 3D model ( JSmol) | |
| |
| |
| (verify) | |
Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Phenindione was introduced in the early 1950s. It acts similar to warfarin, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred. [1] [2]
References
- ^ Naisbitt DJ, Farrell J, Chamberlain PJ, Hopkins JE, Berry NG, Pirmohamed M, Park BK (June 2005). "Characterization of the T-cell response in a patient with phenindione hypersensitivity". The Journal of Pharmacology and Experimental Therapeutics. 313 (3): 1058–65. doi: 10.1124/jpet.105.083758. PMID 15743920. S2CID 17052792.
- ^ Sweetman SC, ed. (2009). Martindale: The Complete Drug Reference (36th ed.). London: Pharmaceutical Press. "Phenindione", p. 1369.
External links
- Diseases Database (DDB): 30536
 | This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it. |
|
| |
| Clinical data | |
|---|---|
| AHFS/ Drugs.com | International Drug Names |
|
Pregnancy category |
|
|
Routes of administration | Oral |
| ATC code | |
| Pharmacokinetic data | |
| Protein binding | 88% |
| Elimination half-life | 5 to 10 hours |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard ( EPA) | |
| ECHA InfoCard | 100.001.323 |
| Chemical and physical data | |
| Formula | C15H10O2 |
| Molar mass | 222.243 g·mol−1 |
| 3D model ( JSmol) | |
| |
| |
| (verify) | |
Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Phenindione was introduced in the early 1950s. It acts similar to warfarin, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred. [1] [2]
References
- ^ Naisbitt DJ, Farrell J, Chamberlain PJ, Hopkins JE, Berry NG, Pirmohamed M, Park BK (June 2005). "Characterization of the T-cell response in a patient with phenindione hypersensitivity". The Journal of Pharmacology and Experimental Therapeutics. 313 (3): 1058–65. doi: 10.1124/jpet.105.083758. PMID 15743920. S2CID 17052792.
- ^ Sweetman SC, ed. (2009). Martindale: The Complete Drug Reference (36th ed.). London: Pharmaceutical Press. "Phenindione", p. 1369.
External links
- Diseases Database (DDB): 30536
|
| This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by expanding it. |