From Wikipedia, the free encyclopedia
  • Comment: Too soon. Just having a single article in Nature is not enough. Ldm1954 ( talk) 16:16, 18 December 2023 (UTC)
  • Comment: External links in text are unsuitbale for wiki. checkY Corrected: Removed and turned into red links. They may be placed in an external links section, but they cannot be a part of the text so as to not spam the reader. microbiologyMarcus ( petri dish· growths) 14:13, 12 December 2023 (UTC)

Monod Bio
Company type Startup company
Industry Biotechnology
FoundersDaniel Adriano Silva Manzano, David Shoultz, Alfredo Quijano Rubio, David Baker
Headquarters
Seattle, Washington
,
Key people
Daniel Adriano Silva Manzano ( CEO), David Shoultz ( COO), Alfredo Quijano Rubio ( CSO)
Website monod.bio

Monod Bio is an American biotechnology company based in Seattle, Washington. The company is developing novel clinical diagnostics and biotechnology tools using AI-powered de novo protein design. [1]

History

The company was founded by Daniel Adriano Silva Manzano, David Shoultz, and Alfredo Quijano Rubio as a spin-out from the University of Washington Institute for Protein Design and the lab of Dr. David Baker. [1] Dr. Baker is a co-founder and close advisor. [1]

It was originally housed in the CoMotion Labs biotech incubator at University of Washington before relocating to a separate facility in South Lake Union. [2] [1] In 2022, Monod Bio completed a seed round financing of $25 million dollars with Matrix Capital Management as a lead investor and participation from the Global Health Investment Corporation Cerano Management, The Washington Research Foundation, Boom Capital Ventures, Sahsen Ventures, and Pack Ventures. [1] [3] [4] [5]

In August 2023, Alfredo Quijano Rubio received Health and Business Insider's 30 under 40 award for his work with the company. [6]

Research

Monod Bio utilizes the " Rosetta" protein engineering software developed at the Institute for Protein Design to develop biosensors. [1] These sensors emit bioluminescent signals in the presence of an analyte, which was showcased in a Nature publication in 2021. [7] The two-protein (known as lucCage and lucKey), modular system emits light when the proteins bind, causing an attached luciferase to emit light. [7]

In December 2022, the lucCage-lucKey biosensor system was featured in a new article in Advanced Materials, where the Baker Lab--featuring CSO, Alfredo Quijano Rubio--collaborated with the Silk Lab at Tufts University. [8] This collaboration theorized the incorporation of the biosensors into silk fibers, allowing for detection of proteins upon contact with the fibers. [8] In February 2023, Monod Bio announced a publication in Nature introducing its de novo protein design platform for the creation of its novel luciferase, LuxSit. [9] [10]

References

  1. ^ a b c d e f Schubert, Charlotte (15 August 2022). "Institute for Protein Design spinout Monod Bio raises $25M for molecular biosensors". GeekWire. Retrieved 7 December 2023.
  2. ^ Schubert, Charlotte (2 August 2023). "Seattle startups move into growing science cluster in South Lake Union". GeekWire. Retrieved 7 December 2023.
  3. ^ Gormley, Brian (15 August 2022). "Biotech Startup Monod Bio Collects $25 Million Seed Financing". Wall Street Journal Venture Capital. Retrieved 7 December 2023.
  4. ^ Pratap, Aayushi (15 August 2022). "David Baker lab spinout scores seed funding to build a biosensor from engineered protein". Endpoints News. Retrieved 7 December 2023.
  5. ^ Vedantam, Keerthi (15 August 2022). "Monod Bio Raises $25M To Quickly Daignose Diseases". Crunchbase News. Retrieved 7 December 2023.
  6. ^ Brueck, Hilary (17 August 2023). "30 Leaders Under 40 Changing Healthcare in 2023". Axel Springer SE. Business Insider. Retrieved 7 December 2023.
  7. ^ a b Quijano-Rubio, Alfredo (27 January 2021). "De novo design of modular and tunable protein biosensors". Nature. 591 (7850): 482–487. doi: 10.1038/s41586-021-03258-z. PMC  8074680. PMID  33503651.
  8. ^ a b d'Amone, Luciana; Matzeu, Guisy; Quijano-Rubio, Alfredo; Callahan, Gregory; Napier, Bradley; Baker, David; Omenetto, Fiorenzo (9 December 2022). "Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection". Advanced Materials. 35 (11). doi: 10.1002/adma.202208556. Retrieved 20 December 2023.
  9. ^ Ha, Kimberely (22 February 2023). "Monod Bio Announces Publication in Nature Highlighting De Novo Protein Technology Platform for the Creation of Novel Luciferases". Berkshire Hathaway. Business Wire. Retrieved 7 December 2023.
  10. ^ Yeh, Andy (22 February 2023). "De novo design of luciferases using deep learning". Nature. 614 (7949): 774–780. doi: 10.1038/s41586-023-05696-3. PMC  9946828. PMID  36813896.
From Wikipedia, the free encyclopedia
  • Comment: Too soon. Just having a single article in Nature is not enough. Ldm1954 ( talk) 16:16, 18 December 2023 (UTC)
  • Comment: External links in text are unsuitbale for wiki. checkY Corrected: Removed and turned into red links. They may be placed in an external links section, but they cannot be a part of the text so as to not spam the reader. microbiologyMarcus ( petri dish· growths) 14:13, 12 December 2023 (UTC)

Monod Bio
Company type Startup company
Industry Biotechnology
FoundersDaniel Adriano Silva Manzano, David Shoultz, Alfredo Quijano Rubio, David Baker
Headquarters
Seattle, Washington
,
Key people
Daniel Adriano Silva Manzano ( CEO), David Shoultz ( COO), Alfredo Quijano Rubio ( CSO)
Website monod.bio

Monod Bio is an American biotechnology company based in Seattle, Washington. The company is developing novel clinical diagnostics and biotechnology tools using AI-powered de novo protein design. [1]

History

The company was founded by Daniel Adriano Silva Manzano, David Shoultz, and Alfredo Quijano Rubio as a spin-out from the University of Washington Institute for Protein Design and the lab of Dr. David Baker. [1] Dr. Baker is a co-founder and close advisor. [1]

It was originally housed in the CoMotion Labs biotech incubator at University of Washington before relocating to a separate facility in South Lake Union. [2] [1] In 2022, Monod Bio completed a seed round financing of $25 million dollars with Matrix Capital Management as a lead investor and participation from the Global Health Investment Corporation Cerano Management, The Washington Research Foundation, Boom Capital Ventures, Sahsen Ventures, and Pack Ventures. [1] [3] [4] [5]

In August 2023, Alfredo Quijano Rubio received Health and Business Insider's 30 under 40 award for his work with the company. [6]

Research

Monod Bio utilizes the " Rosetta" protein engineering software developed at the Institute for Protein Design to develop biosensors. [1] These sensors emit bioluminescent signals in the presence of an analyte, which was showcased in a Nature publication in 2021. [7] The two-protein (known as lucCage and lucKey), modular system emits light when the proteins bind, causing an attached luciferase to emit light. [7]

In December 2022, the lucCage-lucKey biosensor system was featured in a new article in Advanced Materials, where the Baker Lab--featuring CSO, Alfredo Quijano Rubio--collaborated with the Silk Lab at Tufts University. [8] This collaboration theorized the incorporation of the biosensors into silk fibers, allowing for detection of proteins upon contact with the fibers. [8] In February 2023, Monod Bio announced a publication in Nature introducing its de novo protein design platform for the creation of its novel luciferase, LuxSit. [9] [10]

References

  1. ^ a b c d e f Schubert, Charlotte (15 August 2022). "Institute for Protein Design spinout Monod Bio raises $25M for molecular biosensors". GeekWire. Retrieved 7 December 2023.
  2. ^ Schubert, Charlotte (2 August 2023). "Seattle startups move into growing science cluster in South Lake Union". GeekWire. Retrieved 7 December 2023.
  3. ^ Gormley, Brian (15 August 2022). "Biotech Startup Monod Bio Collects $25 Million Seed Financing". Wall Street Journal Venture Capital. Retrieved 7 December 2023.
  4. ^ Pratap, Aayushi (15 August 2022). "David Baker lab spinout scores seed funding to build a biosensor from engineered protein". Endpoints News. Retrieved 7 December 2023.
  5. ^ Vedantam, Keerthi (15 August 2022). "Monod Bio Raises $25M To Quickly Daignose Diseases". Crunchbase News. Retrieved 7 December 2023.
  6. ^ Brueck, Hilary (17 August 2023). "30 Leaders Under 40 Changing Healthcare in 2023". Axel Springer SE. Business Insider. Retrieved 7 December 2023.
  7. ^ a b Quijano-Rubio, Alfredo (27 January 2021). "De novo design of modular and tunable protein biosensors". Nature. 591 (7850): 482–487. doi: 10.1038/s41586-021-03258-z. PMC  8074680. PMID  33503651.
  8. ^ a b d'Amone, Luciana; Matzeu, Guisy; Quijano-Rubio, Alfredo; Callahan, Gregory; Napier, Bradley; Baker, David; Omenetto, Fiorenzo (9 December 2022). "Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection". Advanced Materials. 35 (11). doi: 10.1002/adma.202208556. Retrieved 20 December 2023.
  9. ^ Ha, Kimberely (22 February 2023). "Monod Bio Announces Publication in Nature Highlighting De Novo Protein Technology Platform for the Creation of Novel Luciferases". Berkshire Hathaway. Business Wire. Retrieved 7 December 2023.
  10. ^ Yeh, Andy (22 February 2023). "De novo design of luciferases using deep learning". Nature. 614 (7949): 774–780. doi: 10.1038/s41586-023-05696-3. PMC  9946828. PMID  36813896.

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