Clinical data | |
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Trade names | Cilder, Cloderm, Purantix |
Other names | Clocortolone trimethylacetate; CL-68; SH-863; 9α-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate |
Drug class | Corticosteroid; Glucocorticoid |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.047.099 |
Chemical and physical data | |
Formula | C27H36ClFO5 |
Molar mass | 495.03 g·mol−1 |
3D model ( JSmol) | |
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Clocortolone pivalate (brand names Cilder, Cloderm, Purantix), also known as clocortolone trimethylacetate, is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in the United States and Austria. [1] [2] [3] It is the C21 pivalate (trimethylacetate) ester of clocortolone, [1] [2] and acts as a prodrug of clocortolone in the body. [4] [5]
Clinical data | |
---|---|
Trade names | Cilder, Cloderm, Purantix |
Other names | Clocortolone trimethylacetate; CL-68; SH-863; 9α-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate |
Drug class | Corticosteroid; Glucocorticoid |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.047.099 |
Chemical and physical data | |
Formula | C27H36ClFO5 |
Molar mass | 495.03 g·mol−1 |
3D model ( JSmol) | |
| |
|
Clocortolone pivalate (brand names Cilder, Cloderm, Purantix), also known as clocortolone trimethylacetate, is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in the United States and Austria. [1] [2] [3] It is the C21 pivalate (trimethylacetate) ester of clocortolone, [1] [2] and acts as a prodrug of clocortolone in the body. [4] [5]