Caspase 13 or ERICE ("evolutionarily related interleukin-1β converting enzyme") is a
protein that was identified in
cattle. It belongs to a family of
enzymes called
caspases that cleave their
substrates at
C-terminalaspartic acid residues. Although this enzyme was originally reported as a human caspase that could be activated by
caspase 8,[1] later studies confirmed the gene identified for caspase 13 came from
bovine origin, and is the likely
orthologue of human
caspase 4.[2][3]
^Koenig U, Eckhart L, Tschachler E (2001). "Evidence that caspase-13 is not a human but a bovine gene". Biochem. Biophys. Res. Commun. 285 (5): 1150–4.
doi:
10.1006/bbrc.2001.5315.
PMID11478774.
Caspase 13 or ERICE ("evolutionarily related interleukin-1β converting enzyme") is a
protein that was identified in
cattle. It belongs to a family of
enzymes called
caspases that cleave their
substrates at
C-terminalaspartic acid residues. Although this enzyme was originally reported as a human caspase that could be activated by
caspase 8,[1] later studies confirmed the gene identified for caspase 13 came from
bovine origin, and is the likely
orthologue of human
caspase 4.[2][3]
^Koenig U, Eckhart L, Tschachler E (2001). "Evidence that caspase-13 is not a human but a bovine gene". Biochem. Biophys. Res. Commun. 285 (5): 1150–4.
doi:
10.1006/bbrc.2001.5315.
PMID11478774.