From Wikipedia, the free encyclopedia
Protein-coding gene in humans
Cleavage and polyadenylation specificity factor subunit 7 is a
protein that in humans is encoded by the CPSF7
gene .
[5]
[6]
CPSF7, also known as CFIm59, is the
cleavage factor of two closely associated
protein complexes in the
3' untranslated region of a newly synthesized pre-
messenger RNA (mRNA) molecule used in
gene transcription .
[7] CPSF7 is one of three
Cleavage and polyadenylation specificity factors (CPSF), the other two being CFIm25 (or CPSF5/
NUDT21 ) and CFIm68 (or
CPSF6 ).
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000149532 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000034820 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (December 2002).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proceedings of the National Academy of Sciences of the United States of America . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
^
"Entrez Gene: FLJ12529 pre-mRNA cleavage factor I, 59 kDa subunit" .
^ Hardy JG, Norbury CJ (August 2016).
"Cleavage factor Im (CFIm) as a regulator of alternative polyadenylation" . Biochemical Society Transactions . 44 (4): 1051–7.
doi :
10.1042/BST20160078 .
PMID
27528751 .
S2CID
206156045 .
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006).
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48.
doi :
10.1016/j.cell.2006.09.026 .
PMID
17081983 .
S2CID
7827573 .
Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (May 2006).
"A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" . Cell . 125 (4): 801–14.
doi :
10.1016/j.cell.2006.03.032 .
PMID
16713569 .
S2CID
13709685 .
Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Analytical Chemistry . 76 (10): 2763–72.
doi :
10.1021/ac035352d .
PMID
15144186 .
Rüegsegger U, Beyer K, Keller W (March 1996).
"Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors" . The Journal of Biological Chemistry . 271 (11): 6107–13.
doi :
10.1074/jbc.271.11.6107 .
PMID
8626397 .