From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Centrosomal protein of 135 kDa is a
protein that in humans is encoded by the CEP135
gene .
[5]
[6]
[7]
It is part of the
centrosome throughout the
cell cycle , being distributed in the
pericentriolar material .
[8] CEP135 is required for the centriolar localization of
CEP250 .
[9]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000174799 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000036403 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998).
"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro" . DNA Res . 5 (3): 169–76.
doi :
10.1093/dnares/5.3.169 .
PMID
9734811 .
^ Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (Dec 2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature . 426 (6966): 570–4.
Bibcode :
2003Natur.426..570A .
doi :
10.1038/nature02166 .
PMID
14654843 .
S2CID
4427303 .
^
"Entrez Gene: CEP135 centrosomal protein 135kDa" .
^ Ohta T, Essner R, Ryu JH, Palazzo RE, Uetake Y, Kuriyama R (January 2002).
"Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells" . J. Cell Biol . 156 (1): 87–99.
doi :
10.1083/jcb.200108088 .
PMC
2173569 .
PMID
11781336 .
^ Kim K, Lee S, Chang J, Rhee K (December 2008). "A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization". Exp. Cell Res . 314 (20): 3692–700.
doi :
10.1016/j.yexcr.2008.09.016 .
PMID
18851962 .
External links
Human
CEP135 genome location and
CEP135 gene details page in the
UCSC Genome Browser .
PDBe-KB provides an overview of all the structure information available in the PDB for Human Centrosomal protein of 135 kDa
Further reading
Ewing RM, Chu P, Elisma F, et al. (2007).
"Large-scale mapping of human protein–protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89.
doi :
10.1038/msb4100134 .
PMC
1847948 .
PMID
17353931 .
Olsen JV, Blagoev B, Gnad F, et al. (2006).
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48.
doi :
10.1016/j.cell.2006.09.026 .
PMID
17081983 .
S2CID
7827573 .
Colland F, Jacq X, Trouplin V, et al. (2004).
"Functional Proteomics Mapping of a Human Signaling Pathway" . Genome Res . 14 (7): 1324–32.
doi :
10.1101/gr.2334104 .
PMC
442148 .
PMID
15231748 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Bonaldo MF, Lennon G, Soares MB (1997).
"Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Res . 6 (9): 791–806.
doi :
10.1101/gr.6.9.791 .
PMID
8889548 .