From Wikipedia, the free encyclopedia
α-isabolene synthase
Identifiers
EC no. 4.2.3.38
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

α-Bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-α-bisabolene-forming). [1]

This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate (E)-α-bisabolene + diphosphate

This synthase requires a divalent cation cofactor (Mg2+ or, to a lesser extent, Mn2+) to neutralize the negative charge of the diphosphate leaving group.

References

  1. ^ Bohlmann J, Crock J, Jetter R, Croteau R (June 1998). "Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-alpha-bisabolene synthase from grand fir (Abies grandis)". Proceedings of the National Academy of Sciences of the United States of America. 95 (12): 6756–61. Bibcode: 1998PNAS...95.6756B. doi: 10.1073/pnas.95.12.6756. PMC  22624. PMID  9618485.

External links

From Wikipedia, the free encyclopedia
α-isabolene synthase
Identifiers
EC no. 4.2.3.38
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Search
PMC articles
PubMed articles
NCBI proteins

α-Bisabolene synthase (EC 4.2.3.38, bisabolene synthase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((E)-α-bisabolene-forming). [1]

This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate (E)-α-bisabolene + diphosphate

This synthase requires a divalent cation cofactor (Mg2+ or, to a lesser extent, Mn2+) to neutralize the negative charge of the diphosphate leaving group.

References

  1. ^ Bohlmann J, Crock J, Jetter R, Croteau R (June 1998). "Terpenoid-based defenses in conifers: cDNA cloning, characterization, and functional expression of wound-inducible (E)-alpha-bisabolene synthase from grand fir (Abies grandis)". Proceedings of the National Academy of Sciences of the United States of America. 95 (12): 6756–61. Bibcode: 1998PNAS...95.6756B. doi: 10.1073/pnas.95.12.6756. PMC  22624. PMID  9618485.

External links


Videos

Youtube | Vimeo | Bing

Websites

Google | Yahoo | Bing

Encyclopedia

Google | Yahoo | Bing

Facebook