Combination of | |
---|---|
Adapalene | Retinoid |
Benzoyl peroxide | Peroxide |
Clinical data | |
Trade names | Epiduo, Epiduo Forte |
Routes of administration | Topical |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
KEGG | |
(what is this?) (verify) |
Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of severe acne vulgaris. [1] [2] It consists of a combination of adapalene and benzoyl peroxide in a topical gel formulation. [1] [2]
It is available as a generic medication. [3]
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris. [1] [2]
Commonly reported side effects include the following: [1] [2]
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [4]
The use of adapalene/benzoyl peroxide in combination with oral antibiotics ( lymecycline) has been studied; [5] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).
Combination of | |
---|---|
Adapalene | Retinoid |
Benzoyl peroxide | Peroxide |
Clinical data | |
Trade names | Epiduo, Epiduo Forte |
Routes of administration | Topical |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
KEGG | |
(what is this?) (verify) |
Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of severe acne vulgaris. [1] [2] It consists of a combination of adapalene and benzoyl peroxide in a topical gel formulation. [1] [2]
It is available as a generic medication. [3]
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris. [1] [2]
Commonly reported side effects include the following: [1] [2]
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves. [4]
The use of adapalene/benzoyl peroxide in combination with oral antibiotics ( lymecycline) has been studied; [5] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).