Names | |
---|---|
IUPAC name
5-Deoxy-5-fluoro-D-ribofuranosyl dihydrogen phosphate
| |
Preferred IUPAC name
(2Ξ,3R,4S,5S)-5-(Fluoromethyl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
| |
| |
Properties | |
C5H10FO7P | |
Molar mass | 232.100 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
5-Fluoro-5-deoxy-D-ribose 1-phosphate is metabolite formed during the biosynthesis of organofluorides. It is formed by the purine nucleoside phosphorylase mediated phosphorolytic cleavage of 5'-deoxy-5'-fluoroadenosine. [1] It is isomerized to 5-fluoro-5-deoxy-ribulose-1-phosphate which is then cleaved by an aldolase to release fluoroacetaldehyde. [2]
Names | |
---|---|
IUPAC name
5-Deoxy-5-fluoro-D-ribofuranosyl dihydrogen phosphate
| |
Preferred IUPAC name
(2Ξ,3R,4S,5S)-5-(Fluoromethyl)-3,4-dihydroxyoxolan-2-yl dihydrogen phosphate | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
| |
| |
Properties | |
C5H10FO7P | |
Molar mass | 232.100 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
5-Fluoro-5-deoxy-D-ribose 1-phosphate is metabolite formed during the biosynthesis of organofluorides. It is formed by the purine nucleoside phosphorylase mediated phosphorolytic cleavage of 5'-deoxy-5'-fluoroadenosine. [1] It is isomerized to 5-fluoro-5-deoxy-ribulose-1-phosphate which is then cleaved by an aldolase to release fluoroacetaldehyde. [2]