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Names | |
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IUPAC name
5,7-Dihydroxy-4′-methoxyflavone
| |
Systematic IUPAC name
5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one | |
Other names
5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Linarigenin Acacetine Buddleoflavonol Linarisenin 4′-Methoxyapigenin Apigenin 4′-methyl ether 5,7-Dioxy-4′-methoxyflavone | |
Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.867 |
PubChem
CID
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|
UNII | |
CompTox Dashboard (
EPA)
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|
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Properties | |
C16H12O5 | |
Molar mass | 284.26 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Acacetin is a 4′- O-methylated flavone of the parent compound apigenin, found in Robinia pseudoacacia (black locust), Turnera diffusa (damiana), Betula pendula (silver birch), [1] and in the fern Asplenium normale. [2]
In plant synthesis the enzyme apigenin 4′-O-methyltransferase uses S-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce S-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin).
It shows moderate aromatase inhibition. [3]
![]() | |
![]() | |
Names | |
---|---|
IUPAC name
5,7-Dihydroxy-4′-methoxyflavone
| |
Systematic IUPAC name
5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one | |
Other names
5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Linarigenin Acacetine Buddleoflavonol Linarisenin 4′-Methoxyapigenin Apigenin 4′-methyl ether 5,7-Dioxy-4′-methoxyflavone | |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.006.867 |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C16H12O5 | |
Molar mass | 284.26 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Acacetin is a 4′- O-methylated flavone of the parent compound apigenin, found in Robinia pseudoacacia (black locust), Turnera diffusa (damiana), Betula pendula (silver birch), [1] and in the fern Asplenium normale. [2]
In plant synthesis the enzyme apigenin 4′-O-methyltransferase uses S-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce S-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin).
It shows moderate aromatase inhibition. [3]