2-oxoaldehyde dehydrogenase (NADP+) | |||||||||
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Identifiers | |||||||||
EC no. | 1.2.1.49 | ||||||||
CAS no. | 83588-97-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 2-oxoaldehyde dehydrogenase (NADP+) ( EC 1.2.1.49) is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are 2-oxoaldehyde, NADP+, and H2O, whereas its 3 products are 2-oxo acid, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-oxoaldehyde:NADP+ 2-oxidoreductase. Other names in common use include alpha-ketoaldehyde dehydrogenase, methylglyoxal dehydrogenase, NADP+-linked alpha-ketoaldehyde dehydrogenase, 2-ketoaldehyde dehydrogenase, NADP+-dependent alpha-ketoaldehyde dehydrogenase, and 2-oxoaldehyde dehydrogenase (NADP+). This enzyme participates in pyruvate metabolism.
2-oxoaldehyde dehydrogenase (NADP+) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 1.2.1.49 | ||||||||
CAS no. | 83588-97-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
In enzymology, a 2-oxoaldehyde dehydrogenase (NADP+) ( EC 1.2.1.49) is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are 2-oxoaldehyde, NADP+, and H2O, whereas its 3 products are 2-oxo acid, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-oxoaldehyde:NADP+ 2-oxidoreductase. Other names in common use include alpha-ketoaldehyde dehydrogenase, methylglyoxal dehydrogenase, NADP+-linked alpha-ketoaldehyde dehydrogenase, 2-ketoaldehyde dehydrogenase, NADP+-dependent alpha-ketoaldehyde dehydrogenase, and 2-oxoaldehyde dehydrogenase (NADP+). This enzyme participates in pyruvate metabolism.