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Names | |
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Preferred IUPAC name
Furan-2-carbonyl chloride | |
Other names
2-Furancarbonyl chloride
2-Furancarboxylic acid chloride 2-Furanoyl chloride | |
Identifiers | |
3D model (
JSmol)
|
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ChemSpider | |
ECHA InfoCard | 100.007.658 |
EC Number |
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PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
|
|
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Properties | |
C5H3ClO2 | |
Molar mass | 130.53 g·mol−1 |
Appearance | liquid |
Density | 1.3227 g/mL @ 20 °C |
Melting point | −2 °C (28 °F; 271 K) |
Boiling point | 173 °C (343 °F; 446 K) |
Hazards | |
GHS labelling: | |
![]() ![]() | |
Danger | |
H302, H314 | |
P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2-Furoyl chloride is an acyl chloride of furan. It takes the form of a corrosive liquid, which is more irritating to the eyes than benzoyl chloride. [1] 2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate, an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma. [2]
2-Furoyl chloride was prepared in 1924 by Gelissen by refluxing 2-furoic acid in excess thionyl chloride on a water bath. [1]
2-Furoyl chloride has no major applications but it has been used as a chemical intermediate in the synthesis of various pharmaceuticals; examples include mometasone furoate, [2] fluticasone furoate, [3] diloxanide furoate, [4] Ceftiofur (Excenel), [5] mirfentanil, [6] quinfamide, [7] and diclofurime. [8]
![]() | |
Names | |
---|---|
Preferred IUPAC name
Furan-2-carbonyl chloride | |
Other names
2-Furancarbonyl chloride
2-Furancarboxylic acid chloride 2-Furanoyl chloride | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.007.658 |
EC Number |
|
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C5H3ClO2 | |
Molar mass | 130.53 g·mol−1 |
Appearance | liquid |
Density | 1.3227 g/mL @ 20 °C |
Melting point | −2 °C (28 °F; 271 K) |
Boiling point | 173 °C (343 °F; 446 K) |
Hazards | |
GHS labelling: | |
![]() ![]() | |
Danger | |
H302, H314 | |
P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
2-Furoyl chloride is an acyl chloride of furan. It takes the form of a corrosive liquid, which is more irritating to the eyes than benzoyl chloride. [1] 2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate, an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma. [2]
2-Furoyl chloride was prepared in 1924 by Gelissen by refluxing 2-furoic acid in excess thionyl chloride on a water bath. [1]
2-Furoyl chloride has no major applications but it has been used as a chemical intermediate in the synthesis of various pharmaceuticals; examples include mometasone furoate, [2] fluticasone furoate, [3] diloxanide furoate, [4] Ceftiofur (Excenel), [5] mirfentanil, [6] quinfamide, [7] and diclofurime. [8]